Giorgio Basile1,2, Antonino Catalano3, Giuseppe Mandraffino4, Giuseppe Maltese5, Angela Alibrandi6, Giuliana Ciancio3, Antonino Lasco3, Matteo Cesari7,8,9. 1. Unit of Geriatrics, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria n., Policlinico pad B, 98125, Messina, Italy. giorgio.basile@unime.it. 2. Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France. giorgio.basile@unime.it. 3. Unit of Geriatrics, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria n., Policlinico pad B, 98125, Messina, Italy. 4. Unit of Internal Medicine, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy. 5. Unit for Metabolic Medicine, Cardiovascular Division, King's College London, London, UK. 6. Department of Economics, University of Messina, Messina, Italy. 7. Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France. 8. Université de Toulouse III Paul Sabatier, Toulouse, France. 9. Geriatric Unit, Fondazione Ca' Granda, IRCCS Ospedale Maggiore Policlinico, Milan, Italy.
Abstract
BACKGROUND: The benefits and risks of treating hypertension in old and frail patients are debated. AIM: The aim of the present study is to measure the frailty status in older patients with hypertension and determine the relationships existing between blood pressure (BP) values and frailty. METHODS: Frailty was retrospectively assessed by using the frailty index (FI) in 56 hypertensive old outpatients. Patients with an FI > 0.25 were classified as frail. RESULTS: Forty-five out of 56 (80%) had a FI > 0.25. A statistically significant inverse correlation was found between FI and systolic BP (r = -0.319, p = 0.016), orthostatic systolic BP (r = -0.408, p = 0.002), orthostatic diastolic BP (r = -0.299, p = 0.025), and orthostatic pulse pressure (r = -0.297, p = 0.026). DISCUSSION: Frailer subjects appear as over-treated according to current European guidelines. CONCLUSIONS: FI can play an important role in the clinical setting by supporting the identification of subjects at risk and allowing an improved provision of adapted and personalized care.
BACKGROUND: The benefits and risks of treating hypertension in old and frail patients are debated. AIM: The aim of the present study is to measure the frailty status in older patients with hypertension and determine the relationships existing between blood pressure (BP) values and frailty. METHODS: Frailty was retrospectively assessed by using the frailty index (FI) in 56 hypertensive old outpatients. Patients with an FI > 0.25 were classified as frail. RESULTS: Forty-five out of 56 (80%) had a FI > 0.25. A statistically significant inverse correlation was found between FI and systolic BP (r = -0.319, p = 0.016), orthostatic systolic BP (r = -0.408, p = 0.002), orthostatic diastolic BP (r = -0.299, p = 0.025), and orthostatic pulse pressure (r = -0.297, p = 0.026). DISCUSSION: Frailer subjects appear as over-treated according to current European guidelines. CONCLUSIONS: FI can play an important role in the clinical setting by supporting the identification of subjects at risk and allowing an improved provision of adapted and personalized care.
Authors: Kaiyan Hu; Qi Zhou; Yanbiao Jiang; Zhizhong Shang; Fan Mei; Qianqian Gao; Fei Chen; Li Zhao; Mengyao Jiang; Bin Ma Journal: Biomed Res Int Date: 2021-01-27 Impact factor: 3.411
Authors: Luigina Guasti; Marco Ambrosetti; Marco Ferrari; Franca Marino; Marc Ferrini; Isabella Sudano; Maria Laura Tanda; Iris Parrini; Riccardo Asteggiano; Marco Cosentino Journal: Drugs Aging Date: 2022-07-29 Impact factor: 4.271