Literature DB >> 27873059

The effect of Daikenchuto on postoperative intestinal motility in patients with right-side colon cancer.

Takeshi Yamada1, Satoshi Matsumoto2, Michihiro Koizumi Akihisa Matsuda2, Seiichi Shinji2, Yasuyuki Yokoyama2, Goro Takahashi2, Takuma Iwai2, Kouki Takeda2, Keiichiro Ohta2, Eiji Uchida2.   

Abstract

PURPOSE: Daikenchuto (DKT) has a stimulant effect on intestinal motility and reportedly has a positive effect on postoperative intestinal motility in patients with sigmoid colon cancer. In this study, we investigated the effects of DKT in patients with right-side colon cancer.
METHODS: This retrospective study included 88 patients with right-side colon cancer. We orally administered 7.5 g of DKT in the DKT group and did not administer any DKT to patients in the no-DKT group. All patients ingested radiopaque markers 2 h before surgery, which were used to assess intestinal motility. The postoperative intestinal motility was radiologically assessed by counting the numbers of residual markers in the large and small intestines.
RESULTS: The DKT and no-DKT groups showed no marked differences in the total number of residual markers or number of residual markers in the small intestine. However, in the elderly subgroup, the total number of residual markers in the DKT group was significantly less than in the no-DKT group.
CONCLUSION: Although DKT had some small effect on the postoperative intestinal motility for most patients, it may have positive effects in elderly patients.

Entities:  

Keywords:  Colon cancer; Daikenchuto; Enhanced recovery after surgery

Mesh:

Substances:

Year:  2016        PMID: 27873059     DOI: 10.1007/s00595-016-1449-7

Source DB:  PubMed          Journal:  Surg Today        ISSN: 0941-1291            Impact factor:   2.549


  22 in total

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8.  The effect of traditional Japanese medicine (Kampo) on gastrointestinal function.

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Journal:  Surg Today       Date:  2010-11-26       Impact factor: 2.549

9.  Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study).

Authors:  Hidetoshi Katsuno; Koutarou Maeda; Masatoshi Ohya; Kazuhiko Yoshioka; Akira Tsunoda; Keiji Koda; Hiroyoshi Matsuoka; Hiroki Ohge; Satoshi Morita; Shigetoyo Saji; Takashi Kanematsu; Masaki Kitajima
Journal:  J Gastroenterol       Date:  2015-07-11       Impact factor: 7.527

10.  Safety and efficacy of an "enhanced recovery after surgery" protocol for patients undergoing colon cancer surgery: a multi-institutional controlled study.

Authors:  Hirofumi Ota; Masakazu Ikenaga; Junichi Hasegawa; Kohei Murata; Yasuhiro Miyake; Tsunekazu Mizushima; Taishi Hata; Ichiro Takemasa; Hirofumi Yamamoto; Mitsugu Sekimoto; Riichiro Nezu; Yuichiro Doki; Masaki Mori
Journal:  Surg Today       Date:  2016-09-29       Impact factor: 2.549

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