Literature DB >> 27869489

An atypical presentation of necrotising fasciitis.

K Kunz1, F Seidel1, L Weidhase1, P Hepp2, S Strocka3, T Gradistanac4, S Petros1.   

Abstract

Necrotising fasciitis is a rare infection with a high mortality rate. Clinical manifestation may be influenced by an underlying disease state. We report a case of a 70-year-old man with an anaplastic large-cell lymphoma who presented with inconclusive signs of necrotising fasciitis following a neutropenic phase after chemotherapy. Surgical exploration did not reveal the typical macroscopic features of necrotising fasciitis. Microbiological investigations revealed Escherichia coli. The lack of massive tissue inflammation, probably due to the neutropenia in our patient, has not been described by other authors. Diagnostic uncertainties owing to masked or uncharacteristic signs in immune compromised patients may lead to a delayed surgical debridement, of which clinicians should be aware.

Entities:  

Keywords:  E.Coli; Lymphoma; MTX; Necrotising Fasciitis; Neutropenia

Mesh:

Year:  2016        PMID: 27869489      PMCID: PMC5392849          DOI: 10.1308/rcsann.2016.0348

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  7 in total

1.  Re: 'Enabling the diagnosis of necrotising fasciitis without associated skin changes in a paediatric patient with acute lymphoblastic leukaemia: The LRINEC score'.

Authors:  K C Cahill
Journal:  J Plast Reconstr Aesthet Surg       Date:  2015-03-19       Impact factor: 2.740

2.  Enabling the diagnosis of necrotising fasciitis without associated skin changes in a paediatric patient with acute lymphoblastic leukaemia: the LRINEC score.

Authors:  Christopher Tam Song; Róisín Hamilton; Colin Song; Tze Yean Kong; Steven Lo
Journal:  J Plast Reconstr Aesthet Surg       Date:  2014-08-27       Impact factor: 2.740

Review 3.  Diagnosis and management of necrotising fasciitis: a multiparametric approach.

Authors:  M S Morgan
Journal:  J Hosp Infect       Date:  2010-06-09       Impact factor: 3.926

4.  Analysis of the increasing prevalence of necrotising fasciitis referrals to a regional plastic surgery unit: a retrospective case series.

Authors:  N Hodgins; L Damkat-Thomas; N Shamsian; P Yew; H Lewis; K Khan
Journal:  J Plast Reconstr Aesthet Surg       Date:  2014-11-20       Impact factor: 2.740

5.  The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.

Authors:  Chin-Ho Wong; Lay-Wai Khin; Kien-Seng Heng; Kok-Chai Tan; Cheng-Ooi Low
Journal:  Crit Care Med       Date:  2004-07       Impact factor: 7.598

6.  Improvement of a Clinical Score for Necrotizing Fasciitis: 'Pain Out of Proportion' and High CRP Levels Aid the Diagnosis.

Authors:  Thomas Borschitz; Svenja Schlicht; Ekkehard Siegel; Eric Hanke; Esther von Stebut
Journal:  PLoS One       Date:  2015-07-21       Impact factor: 3.240

Review 7.  Current concepts in the management of necrotizing fasciitis.

Authors:  Evangelos P Misiakos; George Bagias; Paul Patapis; Dimitrios Sotiropoulos; Prodromos Kanavidis; Anastasios Machairas
Journal:  Front Surg       Date:  2014-09-29
  7 in total

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