Literature DB >> 27868021

Rational for targeting the hedgehog signalling pathway in acute myeloid leukemia with FLT3 mutation.

Didier Bouscary1.   

Abstract

Entities:  

Year:  2016        PMID： 27868021      PMCID： PMC5104592          DOI： 10.21037/atm.2016.10.29

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


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  10 in total

1.  Differential expression of Sonic hedgehog and Gli1 in hematological malignancies.

Authors:  L-Y Bai; C-F Chiu; C-W Lin; N-Y Hsu; C-L Lin; W-J Lo; M-C Kao
Journal:  Leukemia       Date:  2007-10-11       Impact factor: 11.528

2.  Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.

Authors:  Cheuk Him Man; Tsz Kan Fung; Christa Ho; Heron H C Han; Howard C H Chow; Alvin C H Ma; William W L Choi; Si Lok; Alice M S Cheung; Connie Eaves; Yok Lam Kwong; Anskar Y H Leung
Journal:  Blood       Date:  2012-02-24       Impact factor: 22.113

3.  Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis.

Authors:  Christian Thiede; Christine Steudel; Brigitte Mohr; Markus Schaich; Ulrike Schäkel; Uwe Platzbecker; Martin Wermke; Martin Bornhäuser; Markus Ritter; Andreas Neubauer; Gerhard Ehninger; Thomas Illmer
Journal:  Blood       Date:  2002-06-15       Impact factor: 22.113

Review 4.  Hedgehog Signal Transduction: Key Players, Oncogenic Drivers, and Cancer Therapy.

Authors:  Ekaterina Pak; Rosalind A Segal
Journal:  Dev Cell       Date:  2016-08-22       Impact factor: 12.270

5.  Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.

Authors:  Yiting Lim; Lukasz Gondek; Li Li; Qiuju Wang; Hayley Ma; Haley Ma; Emily Chang; David L Huso; Sarah Foerster; Luigi Marchionni; Karen McGovern; David Neil Watkins; Craig D Peacock; Mark Levis; Bruce Douglas Smith; Akil A Merchant; Donald Small; William Matsui
Journal:  Sci Transl Med       Date:  2015-06-10       Impact factor: 17.956

6.  Hedgehog signaling is dispensable for adult hematopoietic stem cell function.

Authors:  Jie Gao; Stephanie Graves; Ute Koch; Suqing Liu; Vladimir Jankovic; Silvia Buonamici; Abdeljabar El Andaloussi; Stephen D Nimer; Barbara L Kee; Russell Taichman; Freddy Radtke; Iannis Aifantis
Journal:  Cell Stem Cell       Date:  2009-06-05       Impact factor: 24.633

Review 7.  Hedgehog signaling in cancer stem cells: a focus on hematological cancers.

Authors:  Victoria Campbell; Mhairi Copland
Journal:  Stem Cells Cloning       Date:  2015-01-16

8.  Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation.

Authors:  Christine Dierks; Ronak Beigi; Gui-Rong Guo; Katja Zirlik; Mario R Stegert; Paul Manley; Christopher Trussell; Annette Schmitt-Graeff; Klemens Landwerlin; Hendrik Veelken; Markus Warmuth
Journal:  Cancer Cell       Date:  2008-09-09       Impact factor: 31.743

9.  The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.

Authors:  Hiba Ahmad Zahreddine; Biljana Culjkovic-Kraljacic; Sarit Assouline; Patrick Gendron; Andrea A Romeo; Stephen J Morris; Gregory Cormack; James B Jaquith; Leandro Cerchietti; Eftihia Cocolakis; Abdellatif Amri; Julie Bergeron; Brian Leber; Michael W Becker; Shanshan Pei; Craig T Jordan; Wilson H Miller; Katherine L B Borden
Journal:  Nature       Date:  2014-05-28       Impact factor: 49.962

10.  Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.

Authors:  Nobuaki Fukushima; Yosuke Minami; Seiji Kakiuchi; Yachiyo Kuwatsuka; Fumihiko Hayakawa; Catoriona Jamieson; Hitoshi Kiyoi; Tomoki Naoe
Journal:  Cancer Sci       Date:  2016-09-02       Impact factor: 6.716
  10 in total
  1 in total

1.  The long noncoding RNA TUG1 acts as a competing endogenous RNA to regulate the Hedgehog pathway by targeting miR-132 in hepatocellular carcinoma.

Authors:  Jingjing Li; Qinghui Zhang; Xiaoming Fan; Wenhui Mo; Weiqi Dai; Jiao Feng; Liwei Wu; Tong Liu; Sainan Li; Shizan Xu; Wenwen Wang; Xiya Lu; Qiang Yu; Kan Chen; Yujing Xia; Jie Lu; Yingqun Zhou; Ling Xu; Chuanyong Guo
Journal:  Oncotarget       Date:  2017-07-26
  1 in total

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