Literature DB >> 27868013

Azoramide: a new drug for the treatment of type 2 diabetes?

Carlos Guillen1.   

Abstract

Entities:  

Year:  2016        PMID： 27868013      PMCID： PMC5104614          DOI： 10.21037/atm.2016.10.18

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN： 2305-5839


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  17 in total

1.  Translational control is required for the unfolded protein response and in vivo glucose homeostasis.

Authors:  D Scheuner; B Song; E McEwen; C Liu; R Laybutt; P Gillespie; T Saunders; S Bonner-Weir; R J Kaufman
Journal:  Mol Cell       Date:  2001-06       Impact factor: 17.970

2.  Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes.

Authors:  Umut Ozcan; Erkan Yilmaz; Lale Ozcan; Masato Furuhashi; Eric Vaillancourt; Ross O Smith; Cem Z Görgün; Gökhan S Hotamisligil
Journal:  Science       Date:  2006-08-25       Impact factor: 47.728

Review 3.  The binary switch that controls the life and death decisions of ER stressed β cells.

Authors:  Christine M Oslowski; Fumihiko Urano
Journal:  Curr Opin Cell Biol       Date:  2010-12-16       Impact factor: 8.382

4.  Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

Authors:  Alessandra K Cardozo; Fernanda Ortis; Joachim Storling; Ying-Mei Feng; Joanne Rasschaert; Morten Tonnesen; Françoise Van Eylen; Thomas Mandrup-Poulsen; André Herchuelz; Décio L Eizirik
Journal:  Diabetes       Date:  2005-02       Impact factor: 9.461

5.  Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity.

Authors:  Suneng Fu; Abdullah Yalcin; Grace Y Lee; Ping Li; Jason Fan; Ana Paula Arruda; Benedicte M Pers; Mustafa Yilmaz; Kosei Eguchi; Gökhan S Hotamisligil
Journal:  Sci Transl Med       Date:  2015-06-17       Impact factor: 17.956

Review 6.  The binary switch between life and death of endoplasmic reticulum-stressed beta cells.

Authors:  Christine M Oslowski; Fumihiko Urano
Journal:  Curr Opin Endocrinol Diabetes Obes       Date:  2010-04       Impact factor: 3.243

Review 7.  PERK in the life and death of the pancreatic beta-cell.

Authors:  T P Herbert
Journal:  Biochem Soc Trans       Date:  2007-11       Impact factor: 5.407

8.  In vivo activating transcription factor 3 silencing ameliorates the AMPK compensatory effects for ER stress-mediated β-cell dysfunction during the progression of type-2 diabetes.

Authors:  Ji Yeon Kim; Keun Jae Park; Gyu Hee Kim; Eun Ae Jeong; Dae Yeon Lee; Seong Su Lee; Dae Jin Kim; Gu Seob Roh; Jihyun Song; Sung Hwan Ki; Won-Ho Kim
Journal:  Cell Signal       Date:  2013-08-02       Impact factor: 4.315

9.  Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.

Authors:  Feyza Engin; Alena Yermalovich; Truc Nguyen; Truc Ngyuen; Sarah Hummasti; Wenxian Fu; Decio L Eizirik; Diane Mathis; Gökhan S Hotamisligil
Journal:  Sci Transl Med       Date:  2013-11-13       Impact factor: 17.956

10.  Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Authors:  Daniel A Cunha; Paul Hekerman; Laurence Ladrière; Angie Bazarra-Castro; Fernanda Ortis; Marion C Wakeham; Fabrice Moore; Joanne Rasschaert; Alessandra K Cardozo; Elisa Bellomo; Lutgart Overbergh; Chantal Mathieu; Roberto Lupi; Tsonwin Hai; Andre Herchuelz; Piero Marchetti; Guy A Rutter; Décio L Eizirik; Miriam Cnop
Journal:  J Cell Sci       Date:  2008-06-17       Impact factor: 5.285
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  2 in total

1.  Overdosing on iron: Elevated iron and degenerative brain disorders.

Authors:  Santosh R D'Mello; Mark C Kindy
Journal:  Exp Biol Med (Maywood)       Date:  2020-09-02

Review 2.  Insulin Resistance and Diabetes Mellitus in Alzheimer's Disease.

Authors:  Jesús Burillo; Patricia Marqués; Beatriz Jiménez; Carlos González-Blanco; Manuel Benito; Carlos Guillén
Journal:  Cells       Date:  2021-05-18       Impact factor: 6.600
  2 in total

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