Ashraf Moini1, Manigeh Hedayatshodeh2, Reihaneh Hosseini3, Hadith Rastad4. 1. Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran; Department of Endocrinology and Female Infertility at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran. 2. Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran. 3. Department of Gynecology and Obstetrics, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran. Electronic address: rayh_h@yahoo.com. 4. Research Development Center, Arash Women's Hospital, Tehran University of Medical Sciences, Resalat Highway, Rashid Avenue, Tehran, Iran.
Abstract
OBJECTIVE: A number of factors affect ovarian reserve. In this study, we investigate the association between parity and ovarian reserve in reproductive age women. MATERIALS AND METHODS: This cross-sectional study was conducted on 186 women aged 20-35 years. The participants were divided into two main groups. Group A (n=93) included women with at least one parity (pregnancy after 28 weeks), while group B (n=93) included women with no history of pregnancy. We evaluated the following factors related to ovarian reserve: follicle-stimulating hormone (FSH), ovarian antral follicles, anti-Müllerian hormone (AMH), and ovarian volume. RESULTS: A total of 186 women with a mean age of 27.83±4.49years enrolled in this study. There was a difference in mean AMH between the nulliparous (2.53±1.90ng/ml) and multiparous (3.54±1.42ng/ml) groups (p<0.001). FSH levels were from 5.27±1.8mIU/mL in nulliparous women to 5.01±1.9mIU/mL in multiparous women, which did not significantly differ (p=0.36). Antral follicles and ovarian size in multiparous women increased significantly (p<0.001). CONCLUSION: Parity has a significant association with higher levels of ovarian reserve markers.
OBJECTIVE: A number of factors affect ovarian reserve. In this study, we investigate the association between parity and ovarian reserve in reproductive age women. MATERIALS AND METHODS: This cross-sectional study was conducted on 186 women aged 20-35 years. The participants were divided into two main groups. Group A (n=93) included women with at least one parity (pregnancy after 28 weeks), while group B (n=93) included women with no history of pregnancy. We evaluated the following factors related to ovarian reserve: follicle-stimulating hormone (FSH), ovarian antral follicles, anti-Müllerian hormone (AMH), and ovarian volume. RESULTS: A total of 186 women with a mean age of 27.83±4.49years enrolled in this study. There was a difference in mean AMH between the nulliparous (2.53±1.90ng/ml) and multiparous (3.54±1.42ng/ml) groups (p<0.001). FSH levels were from 5.27±1.8mIU/mL in nulliparous women to 5.01±1.9mIU/mL in multiparous women, which did not significantly differ (p=0.36). Antral follicles and ovarian size in multiparous women increased significantly (p<0.001). CONCLUSION: Parity has a significant association with higher levels of ovarian reserve markers.
Authors: Nydjie P Grimes; Brian W Whitcomb; Katherine W Reeves; Lynnette L Sievert; Alexandra Purdue-Smithe; JoAnn E Manson; Susan E Hankinson; Bernard A Rosner; Elizabeth R Bertone-Johnson Journal: Maturitas Date: 2021-09-20 Impact factor: 4.342
Authors: Ulises Urzúa; Carlos Chacón; Maximiliano Norambuena; Luis Lizama; Sebastián Sarmiento; Esther Asaki; John I Powell; Sandra Ampuero Journal: Biomolecules Date: 2020-01-09
Authors: Tess V Clendenen; Wenzhen Ge; Karen L Koenig; Yelena Afanasyeva; Claudia Agnoli; Elizabeth Bertone-Johnson; Louise A Brinton; Farbod Darvishian; Joanne F Dorgan; A Heather Eliassen; Roni T Falk; Göran Hallmans; Susan E Hankinson; Judith Hoffman-Bolton; Timothy J Key; Vittorio Krogh; Hazel B Nichols; Dale P Sandler; Minouk J Schoemaker; Patrick M Sluss; Malin Sund; Anthony J Swerdlow; Kala Visvanathan; Mengling Liu; Anne Zeleniuch-Jacquotte Journal: J Clin Endocrinol Metab Date: 2021-10-21 Impact factor: 6.134