Literature DB >> 27865274

Screening for Pancreatic Cancer.

Saowanee Ngamruengphong1, Marcia Irene Canto2.   

Abstract

Pancreatic cancer (PC) is a highly fatal disease that can only be cured by complete surgical resection. However, most patients with PC have unresectable disease at the time of diagnosis, highlighting the need to detect PC and its precursor lesions earlier in asymptomatic patients. Screening is not cost-effective for population-based screening of PC. Individuals with genetic risk factors for PC based on family history or known PC-associated genetic syndromes, however, can be a potential target for PC screening programs. This article provides an overview of the epidemiology and genetic background of familial PC and discusses diagnostic and management approaches.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Familial pancreatic cancer; Intraductal papillary mucinous neoplasm; Pancreatic cancer; Pancreatic cyst; Pancreatic intraepithelial neoplasia; Screening

Mesh：

Year:  2016        PMID： 27865274      PMCID： PMC5548103          DOI： 10.1016/j.suc.2016.07.016

Source DB:  PubMed          Journal:  Surg Clin North Am        ISSN： 0039-6109            Impact factor:   2.741


  72 in total

1.  Pancreatic cancer screening in a prospective cohort of high-risk patients: a comprehensive strategy of imaging and genetics.

Authors:  Elizabeth C Verna; Caroline Hwang; Peter D Stevens; Heidrun Rotterdam; Stavros N Stavropoulos; Carolyn D Sy; Martin A Prince; Wendy K Chung; Robert L Fine; John A Chabot; Harold Frucht
Journal:  Clin Cancer Res       Date:  2010-09-28       Impact factor: 12.531

2.  Development of pancreatic cancers during long-term follow-up of side-branch intraductal papillary mucinous neoplasms.

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Journal:  Endoscopy       Date:  2010-11-30       Impact factor: 10.093

3.  Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Authors:  Jian Wu; Hanno Matthaei; Anirban Maitra; Marco Dal Molin; Laura D Wood; James R Eshleman; Michael Goggins; Marcia I Canto; Richard D Schulick; Barish H Edil; Christopher L Wolfgang; Alison P Klein; Luis A Diaz; Peter J Allen; C Max Schmidt; Kenneth W Kinzler; Nickolas Papadopoulos; Ralph H Hruban; Bert Vogelstein
Journal:  Sci Transl Med       Date:  2011-07-20       Impact factor: 17.956

4.  PALB2 mutations in European familial pancreatic cancer families.

Authors:  E P Slater; P Langer; E Niemczyk; K Strauch; J Butler; N Habbe; J P Neoptolemos; W Greenhalf; D K Bartsch
Journal:  Clin Genet       Date:  2010-11       Impact factor: 4.438

5.  Cancer Incidence in BRCA1 mutation carriers.

Authors:  Deborah Thompson; Douglas F Easton
Journal:  J Natl Cancer Inst       Date:  2002-09-18       Impact factor: 13.506

6.  A combination of molecular markers and clinical features improve the classification of pancreatic cysts.

Authors:  Simeon Springer; Yuxuan Wang; Marco Dal Molin; David L Masica; Yuchen Jiao; Isaac Kinde; Amanda Blackford; Siva P Raman; Christopher L Wolfgang; Tyler Tomita; Noushin Niknafs; Christopher Douville; Janine Ptak; Lisa Dobbyn; Peter J Allen; David S Klimstra; Mark A Schattner; C Max Schmidt; Michele Yip-Schneider; Oscar W Cummings; Randall E Brand; Herbert J Zeh; Aatur D Singhi; Aldo Scarpa; Roberto Salvia; Giuseppe Malleo; Giuseppe Zamboni; Massimo Falconi; Jin-Young Jang; Sun-Whe Kim; Wooil Kwon; Seung-Mo Hong; Ki-Byung Song; Song Cheol Kim; Niall Swan; Jean Murphy; Justin Geoghegan; William Brugge; Carlos Fernandez-Del Castillo; Mari Mino-Kenudson; Richard Schulick; Barish H Edil; Volkan Adsay; Jorge Paulino; Jeanin van Hooft; Shinichi Yachida; Satoshi Nara; Nobuyoshi Hiraoka; Kenji Yamao; Susuma Hijioka; Schalk van der Merwe; Michael Goggins; Marcia Irene Canto; Nita Ahuja; Kenzo Hirose; Martin Makary; Matthew J Weiss; John Cameron; Meredith Pittman; James R Eshleman; Luis A Diaz; Nickolas Papadopoulos; Kenneth W Kinzler; Rachel Karchin; Ralph H Hruban; Bert Vogelstein; Anne Marie Lennon
Journal:  Gastroenterology       Date:  2015-08-04       Impact factor: 22.682

7.  The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals.

Authors:  J P Struewing; D Abeliovich; T Peretz; N Avishai; M M Kaback; F S Collins; L C Brody
Journal:  Nat Genet       Date:  1995-10       Impact factor: 38.330

8.  The yield of first-time endoscopic ultrasonography in screening individuals at a high risk of developing pancreatic cancer.

Authors:  J W Poley; I Kluijt; D J Gouma; F Harinck; A Wagner; C Aalfs; C H J van Eijck; A Cats; E J Kuipers; Y Nio; P Fockens; M J Bruno
Journal:  Am J Gastroenterol       Date:  2009-06-02       Impact factor: 10.864

9.  Risk of pancreatic cancer in families with Lynch syndrome.

Authors:  Fay Kastrinos; Bhramar Mukherjee; Nabihah Tayob; Fei Wang; Jennifer Sparr; Victoria M Raymond; Prathap Bandipalliam; Elena M Stoffel; Stephen B Gruber; Sapna Syngal
Journal:  JAMA       Date:  2009-10-28       Impact factor: 56.272

10.  Five years of prospective screening of high-risk individuals from families with familial pancreatic cancer.

Authors:  P Langer; P H Kann; V Fendrich; N Habbe; M Schneider; M Sina; E P Slater; J T Heverhagen; T M Gress; M Rothmund; D K Bartsch
Journal:  Gut       Date:  2009-05-25       Impact factor: 23.059
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  6 in total

Review 1.  White paper on pancreatic ductal adenocarcinoma from society of abdominal radiology's disease-focused panel for pancreatic ductal adenocarcinoma: Part II, update on imaging techniques and screening of pancreatic cancer in high-risk individuals.

Authors:  Naveen M Kulkarni; Lorenzo Mannelli; Marc Zins; Priya R Bhosale; Hina Arif-Tiwari; Olga R Brook; Elizabeth M Hecht; Fay Kastrinos; Zhen Jane Wang; Erik V Soloff; Parag P Tolat; Guillermo Sangster; Jason Fleming; Eric P Tamm; Avinash R Kambadakone
Journal:  Abdom Radiol (NY)       Date:  2020-03

2.  Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.

Authors:  Carrie X Cao; Jeremy M Sharib; Amie M Blanco; Dena Goldberg; Paige Bracci; Rita A Mukhtar; Laura J Esserman; Kimberly S Kirkwood
Journal:  J Am Coll Surg       Date:  2019-10-28       Impact factor: 6.113

3.  Signature of gene aberrant alternative splicing events in pancreatic adenocarcinoma prognosis.

Authors:  Jun Yao; Yu-Chen Tang; Bin Yi; Jian Yang; Yun Chai; Ni Yin; Zi-Xiang Zhang; Yi-Jun Wei; De-Chun Li; Jian Zhou
Journal:  J Cancer       Date:  2021-03-31       Impact factor: 4.207

4.  Fast stimulated Raman and second harmonic generation imaging for intraoperative gastro-intestinal cancer detection.

Authors:  Barbara Sarri; Rafaël Canonge; Xavier Audier; Emma Simon; Julien Wojak; Fabrice Caillol; Cécile Cador; Didier Marguet; Flora Poizat; Marc Giovannini; Hervé Rigneault
Journal:  Sci Rep       Date:  2019-07-11       Impact factor: 4.379

5.  Cell-free DNA TAPS provides multimodal information for early cancer detection.

Authors:  Paulina Siejka-Zielińska; Jingfei Cheng; Felix Jackson; Yibin Liu; Zahir Soonawalla; Srikanth Reddy; Michael Silva; Luminita Puta; Misti Vanette McCain; Emma L Culver; Noor Bekkali; Benjamin Schuster-Böckler; Pier Francesco Palamara; Derek Mann; Helen Reeves; Eleanor Barnes; Shivan Sivakumar; Chun-Xiao Song
Journal:  Sci Adv       Date:  2021-09-01       Impact factor: 14.136

6.  Pre-diagnostic delays caused by gastrointestinal investigations do not affect outcomes in pancreatic cancer.

Authors:  Jeyakumar R Apollos; Sharukh Sami; Manju Nadh Prasanth; Jerusha Jeyakumar; Angus K McFadyen
Journal:  Ann Med Surg (Lond)       Date:  2018-09-10
  6 in total

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