Literature DB >> 27863956

The International Human Epigenome Consortium Data Portal.

David Bujold1, David Anderson de Lima Morais2, Carol Gauthier2, Catherine Côté1, Maxime Caron1, Tony Kwan1, Kuang Chung Chen3, Jonathan Laperle4, Alexei Nordell Markovits5, Tomi Pastinen6, Bryan Caron3, Alain Veilleux2, Pierre-Étienne Jacques7, Guillaume Bourque8.   

Abstract

The International Human Epigenome Consortium (IHEC) coordinates the production of reference epigenome maps through the characterization of the regulome, methylome, and transcriptome from a wide range of tissues and cell types. To define conventions ensuring the compatibility of datasets and establish an infrastructure enabling data integration, analysis, and sharing, we developed the IHEC Data Portal (http://epigenomesportal.ca/ihec). The portal provides access to >7,000 reference epigenomic datasets, generated from >600 tissues, which have been contributed by seven international consortia: ENCODE, NIH Roadmap, CEEHRC, Blueprint, DEEP, AMED-CREST, and KNIH. The portal enhances the utility of these reference maps by facilitating the discovery, visualization, analysis, download, and sharing of epigenomics data. The IHEC Data Portal is the official source to navigate through IHEC datasets and represents a strategy for unifying the distributed data produced by international research consortia. Crown Copyright Â
© 2016. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  API; IHEC; accession; analysis; archival; dataset; epigenomics; metadata; online resource; portal; visualization

Mesh:

Year:  2016        PMID: 27863956     DOI: 10.1016/j.cels.2016.10.019

Source DB:  PubMed          Journal:  Cell Syst        ISSN: 2405-4712            Impact factor:   10.304


  57 in total

1.  Machine Learning for Integrating Data in Biology and Medicine: Principles, Practice, and Opportunities.

Authors:  Marinka Zitnik; Francis Nguyen; Bo Wang; Jure Leskovec; Anna Goldenberg; Michael M Hoffman
Journal:  Inf Fusion       Date:  2018-09-21       Impact factor: 12.975

Review 2.  Druggable Transcriptional Networks in the Human Neurogenic Epigenome.

Authors:  Gerald A Higgins; Aaron M Williams; Alex S Ade; Hasan B Alam; Brian D Athey
Journal:  Pharmacol Rev       Date:  2019-10       Impact factor: 25.468

Review 3.  Translational Perspective on Epigenetics in Cardiovascular Disease.

Authors:  Pim van der Harst; Leon J de Windt; John C Chambers
Journal:  J Am Coll Cardiol       Date:  2017-08-01       Impact factor: 24.094

4.  Complexities of Understanding Function from CKD-Associated DNA Variants.

Authors:  Jennie Lin; Katalin Susztak
Journal:  Clin J Am Soc Nephrol       Date:  2020-06-08       Impact factor: 8.237

Review 5.  Molecular networks in Network Medicine: Development and applications.

Authors:  Edwin K Silverman; Harald H H W Schmidt; Eleni Anastasiadou; Lucia Altucci; Marco Angelini; Lina Badimon; Jean-Luc Balligand; Giuditta Benincasa; Giovambattista Capasso; Federica Conte; Antonella Di Costanzo; Lorenzo Farina; Giulia Fiscon; Laurent Gatto; Michele Gentili; Joseph Loscalzo; Cinzia Marchese; Claudio Napoli; Paola Paci; Manuela Petti; John Quackenbush; Paolo Tieri; Davide Viggiano; Gemma Vilahur; Kimberly Glass; Jan Baumbach
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2020-04-19

Review 6.  Early Detection of Cancer in Blood Using Single-Cell Analysis: A Proposal.

Authors:  Alexander Krasnitz; Jude Kendall; Joan Alexander; Dan Levy; Michael Wigler
Journal:  Trends Mol Med       Date:  2017-06-03       Impact factor: 11.951

Review 7.  Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.

Authors:  Wolfgang Poller; Stefanie Dimmeler; Stephane Heymans; Tanja Zeller; Jan Haas; Mahir Karakas; David-Manuel Leistner; Philipp Jakob; Shinichi Nakagawa; Stefan Blankenberg; Stefan Engelhardt; Thomas Thum; Christian Weber; Benjamin Meder; Roger Hajjar; Ulf Landmesser
Journal:  Eur Heart J       Date:  2018-08-01       Impact factor: 29.983

Review 8.  New insights into the epigenetics of inflammatory rheumatic diseases.

Authors:  Esteban Ballestar; Tianlu Li
Journal:  Nat Rev Rheumatol       Date:  2017-09-14       Impact factor: 20.543

Review 9.  Tales from topographic oceans: topologically associated domains and cancer.

Authors:  Moray J Campbell
Journal:  Endocr Relat Cancer       Date:  2019-11       Impact factor: 5.678

10.  A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection.

Authors:  Alexandre Pellan Cheng; Philip Burnham; John Richard Lee; Matthew Pellan Cheng; Manikkam Suthanthiran; Darshana Dadhania; Iwijn De Vlaminck
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-26       Impact factor: 11.205

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