| Literature DB >> 278630 |
R G Wiggans, R J Jacobson, P J Fialkow, P V Woolley, J S Macdonald, P S Schein.
Abstract
A 64-yr-old female developed acute myeloblastic leukemia following radiation and drug therapy for colon carcinoma. The patient was heterozygous for glucose-6-phosphate dehydrogenase (G-6-PD) and displayed types A and B isoenzymes in nonhematopoietic tissue. In contrast, only type B G-6-PD was observed in peripheral blood white cells. In addition, a karyotypic abnormality was found in peripheral blood and marrow cells but not in skin fibroblasts. The data are consistent with a clonal origin of this leukemia.Entities:
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Year: 1978 PMID: 278630
Source DB: PubMed Journal: Blood ISSN: 0006-4971 Impact factor: 22.113