Literature DB >> 27862766

Terpene Cyclases from Social Amoebae.

Patrick Rabe1, Jan Rinkel1, Britta Nubbemeyer1, Tobias G Köllner2, Feng Chen3, Jeroen S Dickschat1.   

Abstract

Genome sequences of social amoebae reveal the presence of terpene cyclases (TCs) in these organisms. Two TCs from Dictyostelium discoideum converted farnesyl diphosphate into (2S,3R,6S,9S)-(-)-protoillud-7-ene and (3S)-(+)-asterisca-2(9),6-diene. The enzyme mechanisms and EI-MS fragmentations of the products were studied by labeling experiments.
© 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biosynthesis; isotopes; mass spectrometry; social amoebae; terpenes

Mesh：

Substances：

Year:  2016        PMID： 27862766     DOI： 10.1002/anie.201608971

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  16 in total

1.  Using Terpene Synthase Plasticity in Catalysis: On the Enzymatic Conversion of Synthetic Farnesyl Diphosphate Analogues.

Authors:  Anwei Hou; Jeroen S Dickschat
Journal:  Chemistry       Date:  2021-09-29       Impact factor: 5.020

2.  Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds.

Authors:  Hitomi Sasaki; Yuzuru Kubohara; Hirotaka Ishigaki; Katsunori Takahashi; Hiromi Eguchi; Akihiro Sugawara; Yoshiteru Oshima; Haruhisa Kikuchi
Journal:  Molecules       Date:  2020-06-23       Impact factor: 4.411

3.  A terpene synthase-cytochrome P450 cluster in Dictyostelium discoideum produces a novel trisnorsesquiterpene.

Authors:  Xinlu Chen; Katrin Luck; Patrick Rabe; Christopher Qd Dinh; Gad Shaulsky; David R Nelson; Jonathan Gershenzon; Jeroen S Dickschat; Tobias G Köllner; Feng Chen
Journal:  Elife       Date:  2019-05-07       Impact factor: 8.140

4.  Mechanistic Studies on Trichoacorenol Synthase from Amycolatopsis benzoatilytica.

Authors:  Jan Rinkel; Jeroen S Dickschat
Journal:  Chembiochem       Date:  2019-11-07       Impact factor: 3.164

5.  A Family of Related Fungal and Bacterial Di- and Sesterterpenes: Studies on Fusaterpenol and Variediene.

Authors:  Jan Rinkel; Simon T Steiner; Guangkai Bian; Rong Chen; Tiangang Liu; Jeroen S Dickschat
Journal:  Chembiochem       Date:  2019-11-07       Impact factor: 3.164

6.  18-Hydroxydolabella-3,7-diene synthase - a diterpene synthase from Chitinophaga pinensis.

Authors:  Jeroen S Dickschat; Jan Rinkel; Patrick Rabe; Arman Beyraghdar Kashkooli; Harro J Bouwmeester
Journal:  Beilstein J Org Chem       Date:  2017-08-23       Impact factor: 2.883

7.  Diversity and Functional Evolution of Terpene Synthases in Dictyostelid Social Amoebae.

Authors:  Xinlu Chen; Tobias G Köllner; Gad Shaulsky; Qidong Jia; Jeroen S Dickschat; Jonathan Gershenzon; Feng Chen
Journal:  Sci Rep       Date:  2018-09-25       Impact factor: 4.379

8.  Insight into metabolic diversity of the brown-rot basidiomycete Postia placenta responsible for sesquiterpene biosynthesis: semi-comprehensive screening of cytochrome P450 monooxygenase involved in protoilludene metabolism.

Authors:  Hirofumi Ichinose; Takuya Kitaoka
Journal:  Microb Biotechnol       Date:  2018-08-13       Impact factor: 5.813

9.  Genome mining in Trichoderma viride J1-030: discovery and identification of novel sesquiterpene synthase and its products.

Authors:  Xiang Sun; You-Sheng Cai; Yujie Yuan; Guangkai Bian; Ziling Ye; Zixin Deng; Tiangang Liu
Journal:  Beilstein J Org Chem       Date:  2019-08-28       Impact factor: 2.883

10.  Enzymatic Synthesis of Methylated Terpene Analogues Using the Plasticity of Bacterial Terpene Synthases.

Authors:  Anwei Hou; Lukas Lauterbach; Jeroen S Dickschat
Journal:  Chemistry       Date:  2020-01-30       Impact factor: 5.236
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