| Literature DB >> 27862402 |
Ye Zhang1, Yi Zhang1,2, Jeffrey M Burke3, Kristin Gleitsman4, Sarah M Friedrich1, Kelvin J Liu3, Tza-Huei Wang1,5,6,7.
Abstract
An inexpensive, magnetic thermoplastic nanomaterial is developed utilizing a hierarchical layering of micro- and nanoscale silica lamellae to create a high-surface-area and low-shear substrate capable of capturing vast amounts of ultrahigh-molecular-weight DNA. Extraction is performed via a simple 45 min process and is capable of achieving binding capacities up to 1 000 000 times greater than silica microparticles.Entities:
Keywords: high molecular weight; long read sequencing; nanoscale silica; solid-phase extraction; thermoplastic
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Year: 2016 PMID: 27862402 PMCID: PMC5234087 DOI: 10.1002/adma.201603738
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849