Literature DB >> 2786168

Release of VIP- but not CGRP-like immunoreactivity by capsaicin from the human isolated small intestine.

C A Maggi1, P Santicioli, E Del Bianco, P Geppetti, G Barbanti, D Turini, A Meli.   

Abstract

Exposure to capsaicin (1 microM) produced a prompt and sustained release of vasoactive intestinal polypeptide-like immunoreactivity (VIP-LI) from mucosa-free strips of human small intestine (jejunum and ileum). A second application of capsaicin, 60 min later, had no effect indicating complete desensitization, a specific feature of the action of capsaicin on sensory nerves. By contrast no release of calcitonin gene-related peptide (CGRP)-LI was produced upon the first or second application of capsaicin.

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Year:  1989        PMID： 2786168     DOI： 10.1016/0304-3940(89)90421-7

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  3 in total

1.  Intragastric capsaicin stimulates motility of upper gut and proximal colon via distinct pathways in conscious dogs.

Authors:  C Shibata; I Sasaki; H Naito; T Ueno; S Matsuno
Journal:  Dig Dis Sci       Date:  1999-06       Impact factor: 3.199

2.  Human isolated ileum: motor responses of the circular muscle to electrical field stimulation and exogenous neuropeptides.

Authors:  C A Maggi; R Patacchini; P Santicioli; S Giuliani; D Turini; G Barbanti; A Giachetti; A Meli
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-03       Impact factor: 3.000

3.  Calcium Imaging of Nerve-Mast Cell Signaling in the Human Intestine.

Authors:  Sabine Buhner; Natasja Barki; Wolfgang Greiter; Pieter Giesbertz; Ihsan E Demir; Güralp O Ceyhan; Florian Zeller; Hannelore Daniel; Michael Schemann
Journal:  Front Physiol       Date:  2017-11-29       Impact factor: 4.566
  3 in total

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