Literature DB >> 27860304

Nail involvement can predict enthesopathy in patients with psoriasis.

Maria Castellanos-González1, Beatriz Esther Joven2, Julio Sánchez2, Eva María Andrés-Esteban3, Francisco Vanaclocha-Sebastián1, Pablo Ortiz Romero1, Raquel Rivera Díaz1.   

Abstract

BACKGROUND: Although subclinical enthesopathy is a well-established diagnostic criterion for psoriatic arthritis (PsA), it is frequently overlooked, as many patients are asymptomatic. The possibility of finding a clinical clue predicting enthesopathy would help clinicians establish an early diagnosis of PsA.
MATERIAL AND METHODS: A prospective single-center study of a total of 90 patients with psoriasis was conducted to assess the presence of entheseal abnormalities as detected by ultrasound, and to determine any correlation with nail involvement.
RESULTS: Entheseal abnormalities were found in 23 patients (25.5 %), 19 (82.6 %) of whom showed nail involvement, whereas four (17.4 %) individuals did not. Enthesopathy was present in 31.1 % (19/61) of patients with onychopathy compared to 13.8 % (4/29) of those without nail involvement (p  =  0.07). There was a significant correlation between target NAPSI score and evidence of enthesopathy. In addition, the number of nails affected also showed a significant correlation with the presence of enthesopathy (p  = 0.035).
CONCLUSIONS: Clinical evidence of onychopathy may be the clue to an early diagnosis of enthesopathy in psoriasis patients.
© 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Entities:  

Mesh:

Year:  2016        PMID: 27860304     DOI: 10.1111/ddg.12989

Source DB:  PubMed          Journal:  J Dtsch Dermatol Ges        ISSN: 1610-0379            Impact factor:   5.584


  6 in total

Review 1.  Nail psoriasis - what a rheumatologist should know about.

Authors:  Barbara Nieradko-Iwanicka
Journal:  Reumatologia       Date:  2017-03-22

Review 2.  Ultrasound as a useful tool to integrate the clinical assessment of nail involvement in psoriatic arthritis.

Authors:  Jessica Gutierrez-Manjarrez; Marwin Gutierrez; Chiara Bertolazzi; Alfonso Afaro-Rodriguez; Carlos Pineda
Journal:  Reumatologia       Date:  2018-02-28

3.  Ultrasound Assessment of Changes in Nails in Psoriasis and Psoriatic Arthritis.

Authors:  Magdalena Krajewska-Włodarczyk; Agnieszka Owczarczyk-Saczonek; Waldemar Placek; Maja Wojtkiewicz; Andrzej Wiktorowicz; Joanna Wojtkiewicz
Journal:  Biomed Res Int       Date:  2018-09-09       Impact factor: 3.411

4.  Distal interphalangeal joint extensor tendon enthesopathy in patients with nail psoriasis.

Authors:  Magdalena Krajewska-Włodarczyk; Agnieszka Owczarczyk-Saczonek; Waldemar Placek; Maja Wojtkiewicz; Andrzej Wiktorowicz; Joanna Wojtkiewicz
Journal:  Sci Rep       Date:  2019-03-06       Impact factor: 4.379

Review 5.  Improving Imaging Modalities in Early Psoriatic Arthritis: The Role of Ultrasound in Early Diagnosis of Psoriatic Arthritis.

Authors:  Tania Gudu; Beverly Ng; Hannah Jethwa; Catherine Graham; Veda Kudva; Jashmitha Rammanohar; Chen Zhang; Mark Sapsford; Deepak R Jadon
Journal:  Front Med (Lausanne)       Date:  2022-01-07

6.  Predicting the Risk of Psoriatic Arthritis in Plaque Psoriasis Patients: Development and Assessment of a New Predictive Nomogram.

Authors:  Panpan Liu; Yehong Kuang; Li Ye; Cong Peng; Wangqing Chen; Minxue Shen; Mi Zhang; Wu Zhu; Chengzhi Lv; Xiang Chen
Journal:  Front Immunol       Date:  2022-01-20       Impact factor: 7.561

  6 in total

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