| Literature DB >> 27858362 |
Katharina M Schmidt1, Edward K Geissler1, Sven A Lang2.
Abstract
Subcutaneous tumor models are widely used in angiogenesis research. Due to the relative simplicity, these mouse models are ideal for the evaluation of molecular hypotheses. In addition, these models are frequently used to assess anti-angiogenic efficacy during drug development. Finally, subcutaneous models can be performed with either xenogeneic or syngeneic tumors, both harboring advantages and drawbacks. Herein, we describe the use of subcutaneous xenograft models in anticancer research.Entities:
Keywords: Cancer research; Mice; Preclinical anticancer therapy; Tumor angiogenesis; Tumor models; Xenografts
Mesh：
Year: 2016 PMID： 27858362 DOI： 10.1007/978-1-4939-3999-2_12
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745