Literature DB >> 27858255

Cerebellum-from J. E. Purkyně up to Contemporary Research.

František Vožeh1,2.   

Abstract

Jan. Evangelista Purkyně, the most famous among Czech physiologists, was the first who identified and described the largest nerve cells in the cerebellum. The most distinguished researchers of the nervous system then recommended naming these neurons Purkinje cells in his honor. Through experiments by Purkinje and his followers, the function of the cerebellum was properly attributed to the precision of motor movements and skills. This traditional concept was valid until early 1990s, when it was readjusted and replenished with new and important findings. It was discovered that the cerebellar cortex contains more neurons than the cerebral cortex and shortly thereafter was gradually revealed that such enormous numbers of neural cells are not without impact on brain functions. It was shown that the cerebellum, in addition to its traditional role, also participates in higher nervous activity. These new findings were obtained thanks to the introduction of modern methods of examination into the clinical praxis, and experimental procedures using animal models of cerebellar disorders described in this work.

Entities:  

Keywords:  Animal models; Ataxia; Cerebellar degeneration; Cerebellum; Neurodegeneration; Purkinje cells; SCA models

Mesh:

Year:  2017        PMID: 27858255     DOI: 10.1007/s12311-016-0835-4

Source DB:  PubMed          Journal:  Cerebellum        ISSN: 1473-4222            Impact factor:   3.847


  47 in total

1.  Cerebellar projections to the prefrontal cortex of the primate.

Authors:  F A Middleton; P L Strick
Journal:  J Neurosci       Date:  2001-01-15       Impact factor: 6.167

Review 2.  Cerebellar connections: hypothalamus.

Authors:  Filiz Onat; Safiye Cavdar
Journal:  Cerebellum       Date:  2003       Impact factor: 3.847

Review 3.  The cerebellum in feeding control: possible function and mechanism.

Authors:  Jing-Ning Zhu; Jian-Jun Wang
Journal:  Cell Mol Neurobiol       Date:  2007-11-20       Impact factor: 5.046

Review 4.  The role of the cerebellum in schizophrenia.

Authors:  Nancy C Andreasen; Ronald Pierson
Journal:  Biol Psychiatry       Date:  2008-04-08       Impact factor: 13.382

Review 5.  Consensus paper: pathological role of the cerebellum in autism.

Authors:  S Hossein Fatemi; Kimberly A Aldinger; Paul Ashwood; Margaret L Bauman; Charles D Blaha; Gene J Blatt; Abha Chauhan; Ved Chauhan; Stephen R Dager; Price E Dickson; Annette M Estes; Dan Goldowitz; Detlef H Heck; Thomas L Kemper; Bryan H King; Loren A Martin; Kathleen J Millen; Guy Mittleman; Matthew W Mosconi; Antonio M Persico; John A Sweeney; Sara J Webb; John P Welsh
Journal:  Cerebellum       Date:  2012-09       Impact factor: 3.847

6.  Neural design of the cerebellar motor control system.

Authors:  M Ito
Journal:  Brain Res       Date:  1972-05-12       Impact factor: 3.252

7.  Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function.

Authors:  P Bickford
Journal:  Brain Res       Date:  1993-08-20       Impact factor: 3.252

Review 8.  The cerebellum and cognitive function: 25 years of insight from anatomy and neuroimaging.

Authors:  Randy L Buckner
Journal:  Neuron       Date:  2013-10-30       Impact factor: 17.173

9.  Atypical cerebral and cerebellar language organisation: a case study.

Authors:  Kim van Dun; Elke De Witte; Wendy Van Daele; Wim Van Hecke; Mario Manto; Peter Mariën
Journal:  Cerebellum Ataxias       Date:  2015-12-10

Review 10.  From mice to men: lessons from mutant ataxic mice.

Authors:  Jan Cendelin
Journal:  Cerebellum Ataxias       Date:  2014-06-16
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  1 in total

1.  Cerebral Dynamics during the Observation of Point-Light Displays Depicting Postural Adjustments.

Authors:  Eduardo F Martins; Thiago Lemos; Ghislain Saunier; Thierry Pozzo; Daniel Fraiman; Claudia D Vargas
Journal:  Front Hum Neurosci       Date:  2017-05-08       Impact factor: 3.169

  1 in total

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