Literature DB >> 27857967

Temporal regulation of autophagy response by the CULLIN 4-AMBRA1-CULLIN 5 axis.

Manuela Antonioli1, Federica Albiero2, Mauro Piacentini1, Gian Maria Fimia3.   

Abstract

Autophagy controls cell homeostasis and provides a rapid response to a variety of stresses. Although many steps of the autophagy process have been elucidated, how they are temporally regulated is less well characterized. Recently, we reported that dynamic interaction of the pro-autophagic factor AMBRA1 with CULLIN E3 ubiquitin ligases ensures the timely onset and termination of the autophagy response.

Entities:  

Keywords:  AMBRA1; DDB1; DEPTOR; ELONGIN B; autophagy; ubiquitin proteasome system

Year:  2015        PMID： 27857967      PMCID： PMC5068175          DOI： 10.1080/23723556.2015.1008304

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival.

Authors:  Timothy R Peterson; Mathieu Laplante; Carson C Thoreen; Yasemin Sancak; Seong A Kang; W Michael Kuehl; Nathanael S Gray; David M Sabatini
Journal:  Cell       Date:  2009-05-14       Impact factor: 41.582

Review 2.  Autophagy in protein and organelle turnover.

Authors:  N Mizushima
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2011-08-03

Review 3.  Cargo recognition and trafficking in selective autophagy.

Authors:  Alexandra Stolz; Andreas Ernst; Ivan Dikic
Journal:  Nat Cell Biol       Date:  2014-06       Impact factor: 28.824

4.  mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

Authors:  Francesca Nazio; Flavie Strappazzon; Manuela Antonioli; Pamela Bielli; Valentina Cianfanelli; Matteo Bordi; Christine Gretzmeier; Joern Dengjel; Mauro Piacentini; Gian Maria Fimia; Francesco Cecconi
Journal:  Nat Cell Biol       Date:  2013-03-24       Impact factor: 28.824

5.  The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.

Authors:  Sabrina Di Bartolomeo; Marco Corazzari; Francesca Nazio; Serafina Oliverio; Gaia Lisi; Manuela Antonioli; Vittoria Pagliarini; Silvia Matteoni; Claudia Fuoco; Luigi Giunta; Marcello D'Amelio; Roberta Nardacci; Alessandra Romagnoli; Mauro Piacentini; Francesco Cecconi; Gian Maria Fimia
Journal:  J Cell Biol       Date:  2010-10-04       Impact factor: 10.539

Review 6.  Building and remodelling Cullin-RING E3 ubiquitin ligases.

Authors:  John R Lydeard; Brenda A Schulman; J Wade Harper
Journal:  EMBO Rep       Date:  2013-11-15       Impact factor: 8.807

7.  CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis.

Authors:  Liren Liu; Sharrell Lee; Jianxuan Zhang; Sara B Peters; Jeffrey Hannah; Yue Zhang; Yan Yin; Andrew Koff; Liang Ma; Pengbo Zhou
Journal:  Mol Cell       Date:  2009-05-14       Impact factor: 17.970

Review 8.  Autophagosome formation--the role of ULK1 and Beclin1-PI3KC3 complexes in setting the stage.

Authors:  Martina Wirth; Justin Joachim; Sharon A Tooze
Journal:  Semin Cancer Biol       Date:  2013-05-29       Impact factor: 15.707

Review 9.  Ambra1 at the crossroad between autophagy and cell death.

Authors:  G M Fimia; M Corazzari; M Antonioli; M Piacentini
Journal:  Oncogene       Date:  2012-10-15       Impact factor: 9.867

10.  AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics.

Authors:  Manuela Antonioli; Federica Albiero; Francesca Nazio; Tiziana Vescovo; Ariel Basulto Perdomo; Marco Corazzari; Claudia Marsella; Pierluca Piselli; Christine Gretzmeier; Jörn Dengjel; Francesco Cecconi; Mauro Piacentini; Gian Maria Fimia
Journal:  Dev Cell       Date:  2014-12-11       Impact factor: 12.270
  10 in total
  4 in total

1.  AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.

Authors:  Emiliano Maiani; Giacomo Milletti; Francesca Nazio; Søs Grønbæk Holdgaard; Jirina Bartkova; Salvatore Rizza; Valentina Cianfanelli; Mar Lorente; Daniele Simoneschi; Miriam Di Marco; Pasquale D'Acunzo; Luca Di Leo; Rikke Rasmussen; Costanza Montagna; Marilena Raciti; Cristiano De Stefanis; Estibaliz Gabicagogeascoa; Gergely Rona; Nélida Salvador; Emanuela Pupo; Joanna Maria Merchut-Maya; Colin J Daniel; Marianna Carinci; Valeriana Cesarini; Alfie O'sullivan; Yeon-Tae Jeong; Matteo Bordi; Francesco Russo; Silvia Campello; Angela Gallo; Giuseppe Filomeni; Letizia Lanzetti; Rosalie C Sears; Petra Hamerlik; Armando Bartolazzi; Robert E Hynds; David R Pearce; Charles Swanton; Michele Pagano; Guillermo Velasco; Elena Papaleo; Daniela De Zio; Apolinar Maya-Mendoza; Franco Locatelli; Jiri Bartek; Francesco Cecconi
Journal:  Nature       Date:  2021-04-14       Impact factor: 49.962

Review 2.  Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades.

Authors:  Fahd Boutouja; Rebecca Brinkmeier; Thomas Mastalski; Fouzi El Magraoui; Harald W Platta
Journal:  Int J Mol Sci       Date:  2017-11-27       Impact factor: 5.923

3.  Negative Modulation of Macroautophagy by Stabilized HERPUD1 is Counteracted by an Increased ER-Lysosomal Network With Impact in Drug-Induced Stress Cell Survival.

Authors:  Gabriela Vargas; Omar Cortés; Eloisa Arias-Muñoz; Sergio Hernández; Cristobal Cerda-Troncoso; Laura Hernández; Alexis E González; Michael H Tatham; Hianara A Bustamante; Claudio Retamal; Jorge Cancino; Manuel Varas-Godoy; Ronald T Hay; Alejandro Rojas-Fernández; Viviana A Cavieres; Patricia V Burgos
Journal:  Front Cell Dev Biol       Date:  2022-03-02

4.  Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.

Authors:  Francesca Nazio; Francesco Cecconi; Agnese Po; Luana Abballe; Claudio Ballabio; Francesca Diomedi Camassei; Matteo Bordi; Antonio Camera; Simona Caruso; Ignazio Caruana; Marco Pezzullo; Caterina Ferraina; Giacomo Milletti; Matteo Gianesello; Sofia Reddel; Carmen Dolores De Luca; Donatella Ceglie; Sara Marinelli; Silvia Campello; Elena Papaleo; Evelina Miele; Antonella Cacchione; Andrea Carai; Maria Vinci; Enrico Velardi; Biagio De Angelis; Luca Tiberi; Concetta Quintarelli; Angela Mastronuzzi; Elisabetta Ferretti; Franco Locatelli
Journal:  Acta Neuropathol       Date:  2021-07-24       Impact factor: 17.088
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.