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Literature DB >> 2785642

Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected].

L Chatenoud, C Ferran, A Reuter, C Legendre, Y Gevaert, H Kreis, P Franchimont, J F Bach.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 1989 PMID： 2785642 DOI： 10.1056/NEJM198905253202117

Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245

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54 in total

1. Non FcR-binding murine antihuman CD3 monoclonal antibody is capable of productive TCR signalling and induces proliferation in the presence of costimulation.

Authors: R T Meijer; S L Yong; I J ten Berge; R A van Lier; P T Schellekens
Journal: Clin Exp Immunol Date: 2001-03 Impact factor: 4.330

Review 2. Engineered CD3 antibodies for immunosuppression.

Authors: L Renders; T Valerius
Journal: Clin Exp Immunol Date: 2003-09 Impact factor: 4.330

3. Cytokine release and dynamics of leukocyte populations after CD3/TCR monoclonal antibody treatment.

Authors: G J Zlabinger; K M Stuhlmeier; R Eher; S Schmaldienst; R Klauser; A Vychytil; B Watschinger; O Traindl; J Kovarik; E Pohanka
Journal: J Clin Immunol Date: 1992-05 Impact factor: 8.317

4. Phase I trial of a humanized, Fc receptor nonbinding anti-CD3 antibody, hu12F6mu in patients receiving renal allografts.

Authors: Jing Li; Bo Zhou; Jianzhong Shentu; Li Du; Min Tan; Sheng Hou; Weizhu Qian; Bohua Li; Dapeng Zhang; Jianxin Dai; Hao Wang; Xu Zhang; Jianghua Chen; Yajun Guo
Journal: MAbs Date: 2010-07-01 Impact factor: 5.857

Systemic reaction to the anti-T-cell monoclonal antibody OKT3 in relation to serum levels of tumor necrosis factor and interferon-gamma [corrected].

1. Non FcR-binding murine antihuman CD3 monoclonal antibody is capable of productive TCR signalling and induces proliferation in the presence of costimulation.

Review 2. Engineered CD3 antibodies for immunosuppression.

3. Cytokine release and dynamics of leukocyte populations after CD3/TCR monoclonal antibody treatment.

4. Phase I trial of a humanized, Fc receptor nonbinding anti-CD3 antibody, hu12F6mu in patients receiving renal allografts.

Review 5. Cancer therapy with bispecific antibodies: Clinical experience.

Review 6. Tumor necrosis factor and immunopathology.

7. Lethal effect of CD3-specific antibody in mice deficient in TGF-beta1 by uncontrolled flu-like syndrome.

8. Isotype-specific cross-linking of select human Fc gamma R isoforms triggers release of IL-6.

9. Treatment of acute kidney allograft rejection with a non-mitogenic CD3 antibody.

10. In vivo effects of IgA and IgG2a anti-CD3 isotype switch variants.