Fan Li 1 , Honggeng Li 2 , Zhi Xiao 3 , Ronggui Lu 2 , Zhiteng Zhang 1 , Haiyun Zhu 1 , Lihai Ren 4 Show Affiliations »
Abstract
BACKGROUND: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH), subdural hematoma (SDH) and diffuse axonal injury (DAI). METHODS: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage. Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies. RESULTS: Angular velocity and acceleration can be used to predict these injuries and they are the main causation of DAI. Intracranial pressure is the main causation of coup/contrecoup contusion. Shear stress and strain contribute to the rupture of bridging veins that result in SDH, SAH. CONCLUSION: Injury mechanism of intracerebral hemorrhage in vehicle accidents is complicated that with multiple causations. In-depth works need to be carried out in mechanism studies especially for child head injuries. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
BACKGROUND: Intracerebral hemorrhage is one of the most common injuries in vehicle accidents. The aim of this paper is to survey the injury mechanism of intracerebral hemorrhage in vehicle accidents, including contusion, subarachnoid hemorrhage (SAH ), subdural hematoma (SDH) and diffuse axonal injury (DAI). METHODS: A condensed overview is given based on the published studies in biomechanical studies on intracerebral hemorrhage . Animal tests, cadaver tests, accident investigations and numerical simulation are the main method used for the mechanism studies. RESULTS: Angular velocity and acceleration can be used to predict these injuries and they are the main causation of DAI. Intracranial pressure is the main causation of coup/contrecoup contusion. Shear stress and strain contribute to the rupture of bridging veins that result in SDH, SAH . CONCLUSION: Injury mechanism of intracerebral hemorrhage in vehicle accidents is complicated that with multiple causations. In-depth works need to be carried out in mechanism studies especially for child head injuries. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Entities: Disease
Species
Keywords:
Intracerebral hemorrhage; brain injury; passive safety; subarachnoid hemorrhage (SAH); subdural hematomazzm321990(SDH); vehicle accident
Mesh： See more »
Year: 2017
PMID： 27855610 DOI： 10.2174/1381612823666161118144829
Source DB: PubMed Journal: Curr Pharm Des ISSN： 1381-6128 Impact factor: 3.116