Literature DB >> 27855074

Emergence of Colistin Resistance Gene mcr-1 in Cronobacter sakazakii Producing NDM-9 and in Escherichia coli from the Same Animal.

Bao-Tao Liu1, Feng-Jing Song2, Ming Zou3, Zhi-Hui Hao4, Hu Shan1.   

Abstract

We report the presence of mcr-1 in Escherichia coli and carbapenem-resistant Cronobacter sakazakii from the same diseased chicken. The mcr-1 gene linked with ISApl1 was located on two different IncI2 plasmids, including one multidrug plasmid in E. coli, whereas fosA3-blaNDM-9 was on an IncB/O plasmid in C. sakazakii The development of the fosA3-blaNDM-9 resistance region was mediated by IS26 The colocation of mcr-1 or blaNDM-9 with other resistance genes will accelerate the dissemination of the two genes.
Copyright © 2017 American Society for Microbiology.

Entities:  

Keywords:  Cronobacter sakazakii; NDM-9; chicken; insertion sequences; mcr-1

Mesh:

Substances:

Year:  2017        PMID: 27855074      PMCID: PMC5278688          DOI: 10.1128/AAC.01444-16

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  16 in total

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9.  Function Characterization of Endogenous Plasmids in Cronobacter sakazakii and Identification of p-Coumaric Acid as Plasmid-Curing Agent.

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