| Literature DB >> 2785449 |
Abstract
Increased vascular permeability, as measured by changes in skin weight and Evans blue dye extravasation, was produced in the skin after immersion of the anesthetized rat's paw in 12 N hydrochloric, 18N sulfuric, or 14N hydrofluoric acids for 2 min. Corticotropin-releasing factor (CRF), a 41-residue peptide having the rat/human sequence, injected 28 micrograms/kg i.v. 10 min before immersion, was efficacious in reducing these indices of skin injury.Entities:
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Year: 1989 PMID： 2785449 DOI： 10.3109/01480548908999143
Source DB: PubMed Journal: Drug Chem Toxicol ISSN： 0148-0545 Impact factor: 3.356