| Literature DB >> 27853860 |
J M T A Meessen1, W F Peter2, R Wolterbeek3, S C Cannegieter4, C Tilbury2, M R Bénard5, H M J van der Linden2, R Onstenk6, R Tordoir7, S B Vehmeijer6, S H M Verdegaal7, H M Vermeulen8, R G H H Nelissen2, T P M Vliet Vlieland2,9,10.
Abstract
Total hip arthroplasty (THA) and total knee arthroplasty (TKA) bring relief of pain and functional disability to patients with end-stage osteoarthritis, and however, the literature on their impact on patients' level of physical activity (PA) is scarce. Cross-sectional study in patients who underwent THA/TKA surgery in the preceding 6-22 months and a random sample of persons aged >40 years from the Dutch general population, participating in a national survey. PA in minutes per week (min/week) and adherence to the Dutch recommendation for PA (NNGB yes/no) were measured by the short questionnaire to assess health-enhancing PA. Multivariable linear (total min/week) and logistic regression analyses (meeting recommendations PA), adjusting for confounders, were performed for THA and TKA separately. In total, 258 THA [62.3% female, aged 69.4 (9.1)] and 221 TKA [65.7% female, aged 69.5 (8.9)] patients and 4373 persons from the Dutch general population [51.4% female, aged 58.9 (11.6)] were included. The presence of THA was associated after adjusting for age, sex, BMI education and musculoskeletal comorbidities, with more total min/week spent on PA (THA 13.8% increase, 95% CI 1.6-27.6%), whilst both TJA groups were associated with adhering to NNGB (THA: OR 1.79, 95% CI 1.26-2.56; TKA: OR 1.73, 95% CI 1.20-2.51). As this study used questionnaires to compare the PA of THA/TKA patients to the general population, some recall and selection bias might have been induced. After surgery, overall, TJA patients are more likely to adhere NNGB than a representative sample of persons >40 years from the Dutch general population.Entities:
Keywords: Arthroplasty; Osteoarthritis; Physical activity; THA; TKA
Mesh:
Year: 2016 PMID: 27853860 PMCID: PMC5258787 DOI: 10.1007/s00296-016-3598-9
Source DB: PubMed Journal: Rheumatol Int ISSN: 0172-8172 Impact factor: 2.631
Characteristics of patients with total joint arthroplasty and a sample from the general Dutch population
| General Dutch population | Total hip arthroplasty | Total knee arthroplasty | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
| |||||||||||
| Total | # | 4373 | 258 | – | 221 | – | ||||||
| Female | # (%) | 2248 | (51.4%) | 159 | (62.3%) | 0.01 | 144 | (65.7%) | <0.01 | |||
| Age (years) | Mean (SD) | 59 | (11.6) | 69 | (9.1) | <0.01 | 70 | (8.9) | <0.01 | |||
| BMI | Mean (SD) | 26 | (5.0) | 27 | (4.1) | <0.01 | 29 | (5.0) | <0.01 | |||
| Education level | <0.01 | <0.01 | ||||||||||
| Low education | # (%) | 653 | (15.6%) | 75 | (37.3%) | 72 | (41.1%) | |||||
| Medium education | # (%) | 2391 | (57.0%) | 86 | (42.8%) | 81 | (46.3%) | |||||
| High education | # (%) | 1150 | (27.4%) | 40 | (19.9%) | 23 | (12.6%) | |||||
| SF12 | ||||||||||||
| PCS | mean (SD) | 53.9 | (9.4) | 47.6 | (11.2) | <0.01 | 46.6 | (10.8) | <0.01 | |||
| MCS | mean (SD) | 44.1 | (5.0) | 39.8 | (5.2) | <0.01 | 40.6 | (5.1) | <0.01 | |||
| Comorbidities | ||||||||||||
| ≥1 Non-M.Sa | # (%) | 2465 | (57.4%) | ( | 142 | (72.8%) | ( | <0.01 | 138 | (84.1%) | ( | <0.01 |
| ≥1 M.S.b | # (%) | 1224 | (27.9%) | 93 | (39.7%) | ( | <0.01 | 84 | (40.7%) | ( | <0.01 | |
| ≥1 Sensory | # (%) | 400 | (9.3%) | ( | 21 | (8.4%) | ( | 0.736 | 21 | (9.9%) | ( | 0.717 |
Education levels: low (elementary school, lower secondary education); medium (secondary school or college); and high (higher secondary education or university)
BMI body mass index, SF12 Short Form 12, PCS physical component subscale of the SF12, MCS mental component subscale of the SF12
P value is given for a two sample t test or Chi-square between the hip or knee replacement group and the general Dutch population
aNon-musculoskeletal comorbidities
bMusculoskeletal comorbidities
Total minutes per week spent on physical activity per gender, age group for total hip arthroplasty, total knee arthroplasty or general Dutch population
| General Dutch population | Total hip arthroplasty | Total knee arthroplasty | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD |
| Mean | SD |
|
| Mean | SD |
|
| |
| Men | |||||||||||
| Aged <65 | 2846 | 1543 | 2521 | 2722 | 1252 | 32 | 0.692 | 2924 | 1468 | 21 | 0.959 |
| Aged 65–69 | 1976 | 1474 | 414 | 2315 | 1336 | 23 | 0.052 | 2079 | 1316 | 20 | 0.34 |
| Aged 70–74 | 1784 | 1330 | 313 | 2130 | 843 | 20 | 0.003 | 1968 | 1667 | 12 | 0.912 |
| Aged ≥75 | 1461 | 1209 | 372 | 1443 | 1065 | 21 | 0.840 | 2193 | 1477 | 22 | 0.018 |
| Women | |||||||||||
| Aged <65 | 2845 | 1530 | 2761 | 2745 | 1148 | 38 | 0.857 | 2883 | 1695 | 46 | 0.956 |
| Aged 65–69 | 2075 | 1412 | 401 | 2480 | 1908 | 34 | 0.364 | 2048 | 1539 | 25 | 0.764 |
| Aged 70–74 | 1967 | 1273 | 286 | 1867 | 1071 | 33 | 0.888 | 1944 | 2122 | 28 | 0.239 |
| Aged ≥75 | 1449 | 1173 | 525 | 1703 | 1453 | 53 | 0.350 | 1284 | 912 | 45 | 0.577 |
NNGB Nederlandse Norm Gezond Bewegen, Dutch public guideline for physical activity
P value for Mann–Whitely test between the hip arthroplasty group and the general Dutch population
P value for Mann–Whitely test between the knee arthroplasty group and the general Dutch population
P value for Chi-square test between hip arthroplasty group and the general Dutch population
P value for Chi-square test between knee arthroplasty group and the general Dutch population
Fig. 1Stratified representation of total minutes per week physical per week per age group and gender
Regression analyses of min/week and adherence to NNGB
| Total hip arthroplasty | Total knee arthroplasty | |||||||
|---|---|---|---|---|---|---|---|---|
|
| 95% CI |
|
| 95% CI |
| |||
| Total min/week PA | ||||||||
| Univariatea | 1.229 | 1.099 | 1.352 | <0.001 | 1.324 | 1.186 | 1.483 | <0.001 |
| Multivariate 1b | 1.14 | 1.023 | 1.274 | 0.018 | 1.122 | 0.998 | 1.262 | 0.055 |
| Multivariate 2c | 1.138 | 1.016 | 1.276 | 0.024 | 1.112 | 0.986 | 1.256 | 0.084 |
| Adherence to NNGB | ||||||||
| Univariated | 1.487 | 1.111 | 1.989 | 0.008 | 1.289 | 0.952 | 1.745 | 0.101 |
| Multivariate 1e | 1.75 | 1.243 | 2.465 | 0.001 | 1.75 | 1.219 | 2.512 | 0.002 |
| Multivariate 2f | 1.789 | 1.253 | 2.556 | 0.001 | 1.731 | 1.195 | 2.507 | 0.004 |
aUnivariate analysis of total min/week PA ~ arthroplasty
bMultivariate analysis of total min/week PA ~ arthroplasty + age + sex + BMI + education
cMultivariate analysis of total min/week PA ~ arthroplasty + age + sex + BMI + education + musculoskeletal comorbidities
dUnivariate analysis of adherence to NNGB ~ arthroplasty
eMultivariate analysis of adherence to NNGB ~ arthroplasty + age + sex + BMI + education
fMultivariate analysis of adherence to NNGB ~ arthroplasty + age + sex + BMI + education + musculoskeletal comorbidities
Variables statistically significantly associated with min/week physical activity after correcting for age and sex
| General Dutch population | THA | TKA | ||||||
|---|---|---|---|---|---|---|---|---|
| Beta |
| Beta |
| Beta |
| |||
| Total physical activity | ||||||||
| Age | 0.973 | <0.001 | Age | 0.966 | <0.001 | Age | 0.966 | <0.001 |
| Sexa | 0.953 | 0.037 | ||||||
| BMI | 0.995 | 0.022 | BMI | 0.960 | 0.005 | |||
| PCS | 1.016 | <0.001 | ||||||
| Low educationb | 0.774 | <0.001 | ||||||
| Non-M.S. comorbiditiesc | 1.076 | 0.002 | ||||||
| M.S. comorbiditiesd | 1.052 | 0.046 | ||||||
| Sensory comorbiditiese | 1.202 | <0.001 | Sensory comorbiditiese | 1.517 | 0.028 | |||
| Light physical activity | ||||||||
| Age | 0.966 | <0.001 | Age | 0.604 | <0.001 | Age | 0.973 | <0.001 |
| Sexa | 0.748 | <0.001 | Sexa | 0.604 | <0.001 | |||
| BMI | 0.759 | 0.044 | ||||||
| PCS | 1.007 | <0.001 | ||||||
| Low educationb | 0.809 | <0.001 | ||||||
| Medium education | 0.834 | <0.001 | ||||||
| Moderate physical activity | ||||||||
| Age | 0.991 | <0.001 | Age | 0.984 | 0.031 | |||
| Sexa | 1.084 | 0.02 | Sexa | 1.596 | 0.001 | Sexa | 1.538 | 0.009 |
| BMI | 0.912 | 0.022 | BMI | 0.964 | 0.027 | |||
| PCS | 1.016 | <0.001 | ||||||
| MCS | 0.989 | 0.001 | ||||||
| Low educationb | 1.180 | 0.006 | ||||||
| Medium education | 1.384 | <0.001 | ||||||
| Vigorous physical activity | ||||||||
| Age | 1.026 | <0.001 | ||||||
| Sexa | 1.189 | <0.001 | Sexa | 1.489 | 0.005 | Sexa | 1.432 | 0.022 |
| BMI | 0.986 | 0.003 | ||||||
| PCS | 1.014 | <0.001 | PCS | 1.021 | 0.027 | |||
| MCS | 0.957 | 0.008 | ||||||
| Medium educationb | 1.151 | 0.002 | ||||||
aFemales were reference
bHigh education as reference
cAffected with non-musculoskeletal comorbidities persons as reference
dAffected with musculoskeletal comorbidities persons as reference
eAffected with sensory comorbidities persons as reference