Literature DB >> 27852658

Indications for antiviral therapy for chronic hepatitis B in pregnant mothers.

Eric Raeyoon Yoo1, Ryan Babu Perumpail2, George Cholankeril3, Aijaz Ahmed2.   

Abstract

The use of antiviral therapy for chronic hepatitis B virus (HBV) infection in the setting of pregnancy needs to be individualised based on limited data. We report a case of a 34-year-old Korean-American woman with a history of pregnancy with emergent caesarean section due to prolonged labour in the setting of HBV e-antigen (HBeAg) positive chronic HBV with a pretreatment baseline HBV DNA level of 110000 000 million copies per mL. Her first delivery was complicated by mother-to-child transmission (MTCT) of HBV infection to her daughter despite standard active and passive immunoprophylaxis. Our case report highlights an important clinical decision-making step regarding the timing of antiviral therapy in the management of chronic HBV in pregnant women with high risk of MTCT. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID： 27852658      PMCID： PMC5128884          DOI： 10.1136/bcr-2016-217232

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  6 in total

Review 1.  An algorithm for risk assessment and intervention of mother to child transmission of hepatitis B virus.

Authors:  Calvin Q Pan; Zhong-Ping Duan; Kalyan R Bhamidimarri; Huai-Bin Zou; Xiao-Feng Liang; Jie Li; Myron J Tong
Journal:  Clin Gastroenterol Hepatol       Date:  2011-11-09       Impact factor: 11.382

2.  Role of caesarean section in prevention of mother-infant transmission of hepatitis B virus.

Authors:  S D Lee; K J Lo; Y T Tsai; J C Wu; T C Wu; Z L Yang; H T Ng
Journal:  Lancet       Date:  1988-10-08       Impact factor: 79.321

3.  Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load.

Authors:  Calvin Q Pan; Zhongping Duan; Erhei Dai; Shuqin Zhang; Guorong Han; Yuming Wang; Huaihong Zhang; Huaibin Zou; Baoshen Zhu; Wenjing Zhao; Hongxiu Jiang
Journal:  N Engl J Med       Date:  2016-06-16       Impact factor: 91.245

4.  Single-dose tenofovir and emtricitabine for reduction of viral resistance to non-nucleoside reverse transcriptase inhibitor drugs in women given intrapartum nevirapine for perinatal HIV prevention: an open-label randomised trial.

Authors:  Benjamin H Chi; Moses Sinkala; Felistas Mbewe; Ronald A Cantrell; Gina Kruse; Namwinga Chintu; Grace M Aldrovandi; Elizabeth M Stringer; Chipepo Kankasa; Jeffrey T Safrit; Jeffrey S A Stringer
Journal:  Lancet       Date:  2007-11-07       Impact factor: 79.321

5.  The influence of age on the development of the hepatitis B carrier state.

Authors:  W J Edmunds; G F Medley; D J Nokes; A J Hall; H C Whittle
Journal:  Proc Biol Sci       Date:  1993-08-23       Impact factor: 5.349

6.  Reduction of infectivity in chronic hepatitis B virus carriers among healthcare providers and pregnant women by antiviral therapy.

Authors:  Wolfram H Gerlich
Journal:  Intervirology       Date:  2014-07-15       Impact factor: 1.763
  6 in total
  1 in total

1.  Prophylactic effect of tenofovir on viral reactivation in immunocompromised pregnant women living with hepatitis B virus.

Authors:  Le Zhang; Shaoying Yang; Yongfu Yu; Suli Wang; Yuetian Yu; Yi Jin; Aimin Zhao; Yimin Mao; Liangjing Lu
Journal:  Hepatol Commun       Date:  2022-05-20
  1 in total

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