| Literature DB >> 27851922 |
Thomas Simon1, Jonathan S Bromberg2.
Abstract
The role of dendritic cells (DCs) in the induction of antigen-specific tolerance mediated by extrathymic regulatory T (Treg) cells remains incompletely defined. In this issue of Immunity, Jones et al. (2016) show that BTLA+DEC205+CD8+CD11c+ DCs efficiently induce peripheral Treg cells via the engagement of HVEM, a receptor for BTLA.Entities:
Mesh:
Substances:
Year: 2016 PMID: 27851922 DOI: 10.1016/j.immuni.2016.10.030
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745