| Literature DB >> 2784842 |
V Broadbent1, J Pritchard, E Yeomans.
Abstract
Ten children with Langerhans cell histiocytosis (histiocytosis X) either resistant to or intolerant of corticosteroids received etoposide (VP16). Nine responded. In one instance, partial diabetes insipidus was temporarily reversed. There was no major toxicity. Etoposide should be seriously considered as therapy for patients with LCH in whom the toxicity/benefit ratio of steroid therapy is unacceptably high.Entities:
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Year: 1989 PMID： 2784842 DOI： 10.1002/mpo.2950170205
Source DB: PubMed Journal: Med Pediatr Oncol ISSN： 0098-1532