Literature DB >> 27847546

Topical Silicone Sheet Application in the Treatment of Hypertrophic Scars and Keloids.

Iris Westra1, Hth Pham1, Frank B Niessen1.   

Abstract

Objective: Since the early 1980s, topical silicone sheets have been used in the treatment of hypertrophic scars and keloids.This study aimed to determine the optimal duration and application of these sheets. Design: multi-centered therapeutic study. Setting and participants: A total of 224 patients were included in this study; 205 patients with hypertrophic scars and 19 patients with keloids. Patients received treatment with a topical silicone sheet. Treated scars varied in age, ranging from two weeks to 62 years and treatment time ranged from one month to 16 months. Assessment of the scars was performed by the use of standardized study forms and digital photography. Measurements: Skin therapists objectively assessed the scars on its color, thickness, and elasticity. Patients themselves subjectively assessed their perception of their scar and their experience with the usage of the topical silicone sheet.
Results: After applying the topical silicone sheet, all scars, regardless of type of scar and maturity, improved significantly in color, thickness, and elasticity.
Conclusion: In this study, treatment with the topical silicone sheet showed significant improvement on both hypertrophic scars and keloids. Best results were reached when the silicone sheet was applied at least four hours per day.

Entities:  

Year:  2016        PMID: 27847546      PMCID: PMC5104309     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  35 in total

Review 1.  International clinical recommendations on scar management.

Authors:  Thomas A Mustoe; Rodney D Cooter; Michael H Gold; F D Richard Hobbs; Albert-Adrien Ramelet; Peter G Shakespeare; Maurizio Stella; Luc Téot; Fiona M Wood; Ulrich E Ziegler
Journal:  Plast Reconstr Surg       Date:  2002-08       Impact factor: 4.730

Review 2.  Keloids--clinical diagnosis, pathogenesis, and treatment options.

Authors:  Alexander G Marneros; Thomas Krieg
Journal:  J Dtsch Dermatol Ges       Date:  2004-11       Impact factor: 5.584

Review 3.  Topical treatments for hypertrophic scars.

Authors:  Joanna M Zurada; David Kriegel; Ira C Davis
Journal:  J Am Acad Dermatol       Date:  2006-09-18       Impact factor: 11.527

Review 4.  Silicon gel sheeting for preventing and treating hypertrophic and keloid scars.

Authors:  L O'Brien; A Pandit
Journal:  Cochrane Database Syst Rev       Date:  2006-01-25

Review 5.  Scar treatments: preclinical and clinical studies.

Authors:  Richard G Reish; Elof Eriksson
Journal:  J Am Coll Surg       Date:  2008-01-28       Impact factor: 6.113

6.  Prospective, single-blind, randomized, controlled study to assess the efficacy of the 585-nm flashlamp-pumped pulsed-dye laser and silicone gel sheeting in hypertrophic scar treatment.

Authors:  G P Wittenberg; B G Fabian; J L Bogomilsky; L R Schultz; E J Rudner; M L Chaffins; G M Saed; R L Burns; D P Fivenson
Journal:  Arch Dermatol       Date:  1999-09

7.  Evaluation of a self-adherent soft silicone dressing for the treatment of hypertrophic postoperative scars.

Authors:  J I Colom Maján
Journal:  J Wound Care       Date:  2006-05       Impact factor: 2.072

8.  Cica-Care gel sheeting in the management of hypertrophic scarring.

Authors:  S A Carney; C G Cason; J P Gowar; J H Stevenson; J McNee; A R Groves; S S Thomas; N B Hart; P Auclair
Journal:  Burns       Date:  1994-04       Impact factor: 2.744

9.  The use of silicone occlusive sheeting (Sil-K) and silicone occlusive gel (Epiderm) in the prevention of hypertrophic scar formation.

Authors:  F B Niessen; P H Spauwen; P H Robinson; V Fidler; M Kon
Journal:  Plast Reconstr Surg       Date:  1998-11       Impact factor: 4.730

10.  Hypertrophic sternal scars: silicone gel sheet versus Kenalog injection treatment.

Authors:  J E Sproat; A Dalcin; N Weitauer; R S Roberts
Journal:  Plast Reconstr Surg       Date:  1992-12       Impact factor: 4.730

View more
  3 in total

1.  Early Laser for Burn Scars (ELABS): protocol for a multi-centre randomised, controlled trial of both the effectiveness and cost-effectiveness of the treatment of hypertrophic burn scars with Pulsed Dye Laser and standard care compared to standard care alone [version 1; peer review: 2 approved].

Authors:  Mark Brewin; Sharon Docherty; Vanessa Heaslip; Katie Breheny; Jonathon Pleat; Shelley Rhodes; Paul P M van Zuijlen; Mamta Shah
Journal:  NIHR Open Res       Date:  2022-01-18

2.  Scoping Review of Therapeutic Strategies for Keloids and Hypertrophic Scars.

Authors:  Jaclyn B Anderson; Aaron Foglio; Alex B Harrant; Christene A Huang; C Scott Hultman; David W Mathes; Tae W Chong
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-03-22

Review 3.  Silicon-Based Scaffold for Wound Healing Skin Regeneration Applications: A Concise Review.

Authors:  Izzat Zulkiflee; Syafira Masri; Mazlan Zawani; Atiqah Salleh; Ibrahim Nor Amirrah; Mohd Farhanulhakim Mohd Razip Wee; Salma Mohamad Yusop; Mh Busra Fauzi
Journal:  Polymers (Basel)       Date:  2022-10-08       Impact factor: 4.967

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.