Literature DB >> 27846387

Sticking It to the Niche: CD98 Mediates Critical Adhesive Signals in AML.

Andreas Reinisch1, Ravindra Majeti2.   

Abstract

In this issue of Cancer Cell, Bajaj and colleagues report that CD98, a heterodimeric protein highly expressed in acute myeloid leukemia (AML) and largely dispensable for basal hematopoiesis, plays an important role in facilitating leukemia stem cell adhesion to bone marrow vasculature and is a potential therapeutic target in AML.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27846387     DOI： 10.1016/j.ccell.2016.10.014

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  3 in total

1.  Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway.

Authors:  Maho Morimatsu; Erika Yamashita; Shigeto Seno; Takao Sudo; Junichi Kikuta; Hiroki Mizuno; Daisuke Okuzaki; Daisuke Motooka; Masaru Ishii
Journal:  Inflamm Regen       Date:  2020-07-06

2.  Roles and Modalities of Ectonucleotidases in Remodeling the Multiple Myeloma Niche.

Authors:  Antonella Chillemi; Valeria Quarona; Luca Antonioli; Davide Ferrari; Alberto L Horenstein; Fabio Malavasi
Journal:  Front Immunol       Date:  2017-03-20       Impact factor: 7.561

3.  Integrin α7 and Extracellular Matrix Laminin 211 Interaction Promotes Proliferation of Acute Myeloid Leukemia Cells and Is Associated with Granulocytic Sarcoma.

Authors:  Nobuhiko Kobayashi; Tsukasa Oda; Makiko Takizawa; Takuma Ishizaki; Norifumi Tsukamoto; Akihiko Yokohama; Hisashi Takei; Takayuki Saitoh; Hiroaki Shimizu; Kazuki Honma; Kei Kimura-Masuda; Yuko Kuroda; Rei Ishihara; Yuki Murakami; Hirokazu Murakami; Hiroshi Handa
Journal:  Cancers (Basel)       Date:  2020-02-05       Impact factor: 6.639
  3 in total

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