Literature DB >> 27846383

UNRelenting Translation UNRestrains Melanoma Migration.

Ashani T Weeraratna1, Myriam Gorospe2.   

Abstract

The cytoplasmic RNA-binding protein UNR influences key developmental processes by controlling mRNA turnover and translation initiation. In this issue of Cancer Cell, Wurth et al. report that UNR is highly expressed in melanoma and enhances invasion and metastasis at least partly by inducing translation elongation of VIM and RAC1 mRNAs. Published by Elsevier Inc.

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Year:  2016        PMID： 27846383      PMCID： PMC5489341          DOI： 10.1016/j.ccell.2016.10.012

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  Eukaryotic mRNPs may represent posttranscriptional operons.

Authors:  Jack D Keene; Scott A Tenenbaum
Journal:  Mol Cell       Date:  2002-06       Impact factor: 17.970

Review 2.  The human RBPome: from genes and proteins to human disease.

Authors:  Yaseswini Neelamraju; Seyedsasan Hashemikhabir; Sarath Chandra Janga
Journal:  J Proteomics       Date:  2015-05-14       Impact factor: 4.044

Review 3.  Post-transcriptional regulation of gene expression by Unr.

Authors:  Swagat Ray; Pól Ó Catnaigh; Emma C Anderson
Journal:  Biochem Soc Trans       Date:  2015-06       Impact factor: 5.407

4.  Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.

Authors:  K Vuoriluoto; H Haugen; S Kiviluoto; J-P Mpindi; J Nevo; C Gjerdrum; C Tiron; J B Lorens; J Ivaska
Journal:  Oncogene       Date:  2010-11-08       Impact factor: 9.867

5.  UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis.

Authors:  Laurence Wurth; Panagiotis Papasaikas; David Olmeda; Nadine Bley; Guadalupe T Calvo; Santiago Guerrero; Daniela Cerezo-Wallis; Javier Martinez-Useros; María García-Fernández; Stefan Hüttelmaier; Maria S Soengas; Fátima Gebauer
Journal:  Cancer Cell       Date:  2016-10-27       Impact factor: 31.743

Review 6.  Regulation of the expression and activity of Unr in mammalian cells.

Authors:  Emma C Anderson; Pól Ó Catnaigh
Journal:  Biochem Soc Trans       Date:  2015-12       Impact factor: 5.407

Review 7.  RNA-binding proteins and post-transcriptional gene regulation.

Authors:  Tina Glisovic; Jennifer L Bachorik; Jeongsik Yong; Gideon Dreyfuss
Journal:  FEBS Lett       Date:  2008-03-13       Impact factor: 4.124

Review 8.  The involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cells.

Authors:  Or-Yam Revach; Sabina E Winograd-Katz; Yardena Samuels; Benjamin Geiger
Journal:  Exp Cell Res       Date:  2016-02-10       Impact factor: 3.905

9.  Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance.

Authors:  Kari R Fischer; Anna Durrans; Sharrell Lee; Jianting Sheng; Fuhai Li; Stephen T C Wong; Hyejin Choi; Tina El Rayes; Seongho Ryu; Juliane Troeger; Robert F Schwabe; Linda T Vahdat; Nasser K Altorki; Vivek Mittal; Dingcheng Gao
Journal:  Nature       Date:  2015-11-11       Impact factor: 49.962
  9 in total

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