Literature DB >> 27846382

Cholesterol: An Achilles' Heel for Glioblastoma?

Zhenyi An1, William A Weiss2.   

Abstract

In this issue of Cancer Cell, Villa et al. report that survival of glioblastoma cells is dependent on uptake of cholesterol. A synthetic agonist of the Liver X receptor depleted cholesterol in GBM cells, slowing growth of GBM xenografts.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27846382     DOI： 10.1016/j.ccell.2016.10.011

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  7 in total

1.  Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma.

Authors:  Risheng Yang; Yuanlin Zhao; Yu Gu; Ying Yang; Xing Gao; Yuan Yuan; Liming Xiao; Jin Zhang; Chao Sun; Han Yang; Junhui Qin; Jing Li; Feng Zhang; Lijun Zhang; Jing Ye
Journal:  Oncogene       Date:  2020-08-27       Impact factor: 9.867

2.  Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma.

Authors:  Mingzhi Han; Shuai Wang; Ning Yang; Xu Wang; Wenbo Zhao; Halala Sdik Saed; Thomas Daubon; Bin Huang; Anjing Chen; Gang Li; Hrvoje Miletic; Frits Thorsen; Rolf Bjerkvig; Xingang Li; Jian Wang
Journal:  EMBO Mol Med       Date:  2019-11-28       Impact factor: 12.137

Review 3.  Cancer metabolism and intervention therapy.

Authors:  Huakan Zhao; Yongsheng Li
Journal:  Mol Biomed       Date:  2021-02-20

4.  Neurotherapeutic implications of sense and respond strategies generated by astrocytes and astrocytic tumours to combat pH mechanical stress.

Authors:  Sebastian John; Gayathri K G; Aswani P Krishna; Rashmi Mishra
Journal:  Neuropathol Appl Neurobiol       Date:  2021-12-09       Impact factor: 6.250

Review 5.  Metabolic Drivers of Invasion in Glioblastoma.

Authors:  Joseph H Garcia; Saket Jain; Manish K Aghi
Journal:  Front Cell Dev Biol       Date:  2021-07-01

6.  Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System

Authors:  Nimisha Saxena; Amar Preet Kaur; Nimai Chand Chandra
Journal:  Asian Pac J Cancer Prev       Date:  2018-01-27

7.  A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates.

Authors:  Zuzana Saidak; Christophe Louandre; Samy Dahmani; Chloé Sauzay; Sara Guedda; Bruno Chauffert; Denis Chatelain; Irene Ceballos-Picot; Antoine Galmiche
Journal:  Biosci Rep       Date:  2018-09-19       Impact factor: 3.840
  7 in total

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