Literature DB >> 27846188

Osteosarcoma: Accurately diagnosing this bone-chilling disease.

Chelsea Hiller1, Jennifer L Wegler, Christopher P Forest.   

Abstract

Osteosarcoma is the most common primary bone malignancy in children and adolescents. Because the incidence of osteosarcoma is low and the disease occurs in physically active patients, it may be misdiagnosed as a more benign condition, thus leading to late diagnosis. This article describes the disease's most frequent presenting complaints and initial radiographic findings, as well as its risk factors and common misdiagnoses. Clinicians should consider osteosarcoma in young patients with persistent bone pain, especially pain with weight-bearing.

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Year:  2016        PMID: 27846188     DOI: 10.1097/01.JAA.0000508202.17804.4d

Source DB:  PubMed          Journal:  JAAPA        ISSN: 0893-7400


  4 in total

1.  Standard Treatment Remains the Recommended Approach for Patients with Bone Sarcoma Who Underwent Unplanned Surgery: Report from the Japanese Musculoskeletal Oncology Group.

Authors:  Tomoki Nakamura; Jun Sugaya; Norifumi Naka; Hiroshi Kobayashi; Tomotake Okuma; Toshiyuki Kunisada; Kunihiro Asanuma; Hedetatsu Outani; Shunji Nishimura; Hiroyuki Kawashima; Toru Akiyama; Taketoshi Yasuda; Shinji Miwa; Akihiro Sudo; Takafumi Ueda
Journal:  Cancer Manag Res       Date:  2020-10-12       Impact factor: 3.989

2.  PAK5 overexpression is associated with lung metastasis in osteosarcoma.

Authors:  Kun Han; Yan Zhou; Kuo-Fu Tseng; Haiyan Hu; Kunpeng Li; Yaling Wang; Zhihua Gan; Shuchen Lin; Yongning Sun; Daliu Min
Journal:  Oncol Lett       Date:  2017-12-07       Impact factor: 2.967

3.  In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/β-catenin signaling pathway in osteosarcoma.

Authors:  Zhi-Cai Zhang; Jian-Xiang Liu; Zeng-Wu Shao; Fei-Fei Pu; Bai-Chuan Wang; Qiang Wu; Yu-Kun Zhang; Xian-Lin Zeng; Xiao-Dong Guo; Shu-Hua Yang; Tong-Chuan He
Journal:  Medicine (Baltimore)       Date:  2017-07       Impact factor: 1.889

4.  Suppressing STAT5 signaling affects osteosarcoma growth and stemness.

Authors:  Dharmalingam Subramaniam; Pablo Angulo; Sivapriya Ponnurangam; Prasad Dandawate; Prabhu Ramamoorthy; Pugazhendhi Srinivasan; Tomoo Iwakuma; Scott J Weir; Katherine Chastain; Shrikant Anant
Journal:  Cell Death Dis       Date:  2020-02-24       Impact factor: 8.469

  4 in total

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