Literature DB >> 27845589

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

Marrah E Lachowicz-Scroggins1, Shaopeng Yuan2, Sheena C Kerr1, Eleanor M Dunican1, Michelle Yu1, Stephen D Carrington3, John V Fahy1.   

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Year:  2016        PMID： 27845589      PMCID： PMC5114443          DOI： 10.1164/rccm.201603-0526LE

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  10 in total

1.  T-helper type 2-driven inflammation defines major subphenotypes of asthma.

Authors:  Prescott G Woodruff; Barmak Modrek; David F Choy; Guiquan Jia; Alexander R Abbas; Almut Ellwanger; Laura L Koth; Joseph R Arron; John V Fahy
Journal:  Am J Respir Crit Care Med       Date:  2009-05-29       Impact factor: 21.405

2.  Heterogeneity of airways mucus: variations in the amounts and glycoforms of the major oligomeric mucins MUC5AC and MUC5B.

Authors:  Sara Kirkham; John K Sheehan; David Knight; Paul S Richardson; David J Thornton
Journal:  Biochem J       Date:  2002-02-01       Impact factor: 3.857

Review 3.  Goblet cell and mucin gene abnormalities in asthma.

Authors:  John V Fahy
Journal:  Chest       Date:  2002-12       Impact factor: 9.410

4.  Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma.

Authors:  Sheena C Kerr; Stephen D Carrington; Stefan Oscarson; Mary E Gallagher; Margaret Solon; Shaopeng Yuan; Jacqueline N Ahn; Ryan H Dougherty; Walter E Finkbeiner; Michael C Peters; John V Fahy
Journal:  Am J Respir Crit Care Med       Date:  2014-04-15       Impact factor: 21.405

5.  Muc5b is required for airway defence.

Authors:  Michelle G Roy; Alessandra Livraghi-Butrico; Ashley A Fletcher; Melissa M McElwee; Scott E Evans; Ryan M Boerner; Samantha N Alexander; Lindsey K Bellinghausen; Alfred S Song; Youlia M Petrova; Michael J Tuvim; Roberto Adachi; Irlanda Romo; Andrea S Bordt; M Gabriela Bowden; Joseph H Sisson; Prescott G Woodruff; David J Thornton; Karine Rousseau; Maria M De la Garza; Seyed J Moghaddam; Harry Karmouty-Quintana; Michael R Blackburn; Scott M Drouin; C William Davis; Kristy A Terrell; Barbara R Grubb; Wanda K O'Neal; Sonia C Flores; Adela Cota-Gomez; Catherine A Lozupone; Jody M Donnelly; Alan M Watson; Corinne E Hennessy; Rebecca C Keith; Ivana V Yang; Lea Barthel; Peter M Henson; William J Janssen; David A Schwartz; Richard C Boucher; Burton F Dickey; Christopher M Evans
Journal:  Nature       Date:  2013-12-08       Impact factor: 49.962

6.  Comparison of two methods of collecting induced sputum in asthmatic subjects.

Authors:  N H Gershman; H H Wong; J T Liu; M J Mahlmeister; J V Fahy
Journal:  Eur Respir J       Date:  1996-12       Impact factor: 16.671

7.  Oxidation increases mucin polymer cross-links to stiffen airway mucus gels.

Authors:  Shaopeng Yuan; Martin Hollinger; Marrah E Lachowicz-Scroggins; Sheena C Kerr; Eleanor M Dunican; Brian M Daniel; Sudakshina Ghosh; Serpel C Erzurum; Belinda Willard; Stanley L Hazen; Xiaozhu Huang; Stephen D Carrington; Stefan Oscarson; John V Fahy
Journal:  Sci Transl Med       Date:  2015-02-25       Impact factor: 17.956

8.  Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.

Authors:  Takumi Kiwamoto; Toshihiko Katoh; Michael Tiemeyer; Bruce S Bochner; Christopher M Evans; William J Janssen; Mary E Brummet; Sherry A Hudson; Zhou Zhu
Journal:  J Allergy Clin Immunol       Date:  2014-12-12       Impact factor: 10.793

9.  Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma.

Authors:  Anh L Innes; Stephen D Carrington; David J Thornton; Sara Kirkham; Karine Rousseau; Ryan H Dougherty; Wilfred W Raymond; George H Caughey; Susan J Muller; John V Fahy
Journal:  Am J Respir Crit Care Med       Date:  2009-05-07       Impact factor: 21.405

10.  The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

Authors:  Christopher M Evans; Dorota S Raclawska; Fani Ttofali; Deborah R Liptzin; Ashley A Fletcher; Daniel N Harper; Maggie A McGing; Melissa M McElwee; Olatunji W Williams; Elizabeth Sanchez; Michelle G Roy; Kristen N Kindrachuk; Thomas A Wynn; Holger K Eltzschig; Michael R Blackburn; Michael J Tuvim; William J Janssen; David A Schwartz; Burton F Dickey
Journal:  Nat Commun       Date:  2015-02-17       Impact factor: 14.919
  10 in total
  46 in total

1.  Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid.

Authors:  Leah R Reznikov; Yan Shin J Liao; Tongjun Gu; Katelyn M Davis; Shin Ping Kuan; Kalina R Atanasova; Joshua S Dadural; Emily N Collins; Maria V Guevara; Kevin Vogt
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2018-11-08       Impact factor: 5.464

2.  Gel-forming mucins form distinct morphologic structures in airways.

Authors:  Lynda S Ostedgaard; Thomas O Moninger; James D McMenimen; Nicholas M Sawin; Connor P Parker; Ian M Thornell; Linda S Powers; Nicholas D Gansemer; Drake C Bouzek; Daniel P Cook; David K Meyerholz; Mahmoud H Abou Alaiwa; David A Stoltz; Michael J Welsh
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-12       Impact factor: 11.205

Review 3.  Airway Mucin Secretion.

Authors:  Ana M Jaramillo; Zoulikha Azzegagh; Michael J Tuvim; Burton F Dickey
Journal:  Ann Am Thorac Soc       Date:  2018-11

Review 4.  Intracellular Processing of Human Secreted Polymeric Airway Mucins.

Authors:  David J Thornton; Catherine Sharpe; Caroline Ridley
Journal:  Ann Am Thorac Soc       Date:  2018-11

5.  A Slippery Cause of a Slimy Problem: Mucin Induction by an Esterified Lipid.

Authors:  Scott H Randell; Darryl C Zeldin
Journal:  Am J Respir Cell Mol Biol       Date:  2017-12       Impact factor: 6.914

6.  Airway Mucin Concentration as a Marker of Chronic Bronchitis.

Authors:  Mehmet Kesimer; Amina A Ford; Agathe Ceppe; Giorgia Radicioni; Rui Cao; C William Davis; Claire M Doerschuk; Neil E Alexis; Wayne H Anderson; Ashley G Henderson; R Graham Barr; Eugene R Bleecker; Stephanie A Christenson; Christopher B Cooper; MeiLan K Han; Nadia N Hansel; Annette T Hastie; Eric A Hoffman; Richard E Kanner; Fernando Martinez; Robert Paine; Prescott G Woodruff; Wanda K O'Neal; Richard C Boucher
Journal:  N Engl J Med       Date:  2017-09-07       Impact factor: 91.245

7.  Interleukin-13 Stimulation Reveals the Cellular and Functional Plasticity of the Airway Epithelium.

Authors:  Max A Seibold
Journal:  Ann Am Thorac Soc       Date:  2018-04

Review 8.  Etiology of epithelial barrier dysfunction in patients with type 2 inflammatory diseases.

Authors:  Robert P Schleimer; Sergejs Berdnikovs
Journal:  J Allergy Clin Immunol       Date:  2017-06       Impact factor: 10.793

9.  Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1.

Authors:  Lauren J Donoghue; Alessandra Livraghi-Butrico; Kathryn M McFadden; Joseph M Thomas; Gang Chen; Barbara R Grubb; Wanda K O'Neal; Richard C Boucher; Samir N P Kelada
Journal:  Genetics       Date:  2017-08-29       Impact factor: 4.562

10.  [Receptor for advanced glycation end products upregulates MUC5AC expression and promotes mucus overproduction in mice with toluene diisocyanate-induced asthma].

Authors:  Jing Xiong; Wen-Qu Zhao; Guo-Hua Huang; Li-Hong Yao; Hang-Ming Dong; Chang-Hui Yu; Hai-Jin Zhao; Shao-Xi Cai
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2017-10-20
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