Irene Karam1, Min Yao2, Dwight E Heron3, Ian Poon1, Shlomo A Koyfman4, Sue S Yom5, Farzan Siddiqui6, Eric Lartigau7, Mustafa Cengiz8, Hideya Yamazaki9, Wendy Hara10, Jack Phan11, John A Vargo3, Victor Lee12, Robert L Foote13, K William Harter14, Nancy Y Lee15, Arjun Sahgal1, Simon S Lo16. 1. Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Science Center, University of Toronto, Toronto, ON, Canada. 2. Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland, OH, USA. 3. Department of Radiation Oncology, Otolaryngology, Head & Neck Surgery, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA. 4. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA. 5. Department of Radiation Oncology, University of California, San Francisco, CA, USA. 6. Department of Radiation Oncology, Henry Ford Health System, Detroit, MI, USA. 7. Department of Radiation Oncology, Centre Oscar Lambret, Lille, France. 8. Department of Radiation Oncology, Hacettepe University, Ankara, Turkey. 9. Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan. 10. Department of Radiation Oncology, Stanford University, Stanford, CA, USA. 11. Department of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USA. 12. Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China. 13. Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA. 14. Department of Radiation Oncology, Georgetown University & Vincent T Lombardi Comprehensive Cancer Center, Washington, DC, USA. 15. Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. 16. Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA.
Abstract
AIM: To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. MATERIALS & METHODS: 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. RESULTS: SBRT is used 10-100% of the time for recurrent primary head and neck cancer, and 0-10% of the time in newly diagnosed disease. Five centers use a constraint for primary disease of 3-5 cm and 25-30 cc. Nine institutions apply a clinical target volume expansion of 1-10 mm and 14 use a planning target volume margin of 1-5 mm. Fractionation regimens vary between 15 and 22 Gy in 1 fraction to 30-50 Gy in 5 or 6 fractions. The risk of carotid blowout quoted in the re-irradiation setting ranges from 3 to 20%. CONCLUSION: There is considerable heterogeneity in patient selection and techniques in head and neck SBRT practice among experienced centers.
AIM: To provide a multi-institutional description of current practices of stereotactic body radiotherapy (SBRT) for head and neck cancer. MATERIALS & METHODS: 15 international institutions with significant experience in head and neck SBRT were asked to complete a questionnaire covering clinical and technical factors. RESULTS: SBRT is used 10-100% of the time for recurrent primary head and neck cancer, and 0-10% of the time in newly diagnosed disease. Five centers use a constraint for primary disease of 3-5 cm and 25-30 cc. Nine institutions apply a clinical target volume expansion of 1-10 mm and 14 use a planning target volume margin of 1-5 mm. Fractionation regimens vary between 15 and 22 Gy in 1 fraction to 30-50 Gy in 5 or 6 fractions. The risk of carotid blowout quoted in the re-irradiation setting ranges from 3 to 20%. CONCLUSION: There is considerable heterogeneity in patient selection and techniques in head and neck SBRT practice among experienced centers.
Entities:
Keywords:
SBRT; ablation; head and neck cancer; patterns of practice; stereotactic
Authors: J Boustani; A Ruffier; A Moya-Plana; Y Tao; F Nguyen; C Even; C Berthold; O Casiraghi; S Temam; P Blanchard Journal: Strahlenther Onkol Date: 2020-06-08 Impact factor: 3.621
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