| Literature DB >> 27841590 |
Yuji Sakai1,2, Masashi Tachikawa2, Atsushi Mochizuki2.
Abstract
We report molecular dynamics simulations of the segregation of two overlapping polymers motivated by chromosome segregation in biological cells. We investigate the relationship between polymer shapes and segregation dynamics and show that elongation and compaction make entangled polymers segregate rapidly. This result suggests that eukaryotic chromosomes take such a characteristic rod-shaped structure, which is induced by condensins, to achieve rapid segregation.Entities:
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Year: 2016 PMID: 27841590 DOI: 10.1103/PhysRevE.94.042403
Source DB: PubMed Journal: Phys Rev E ISSN: 2470-0045 Impact factor: 2.529