Literature DB >> 2784063

The protein CDP, but not CP1, footprints on the CCAAT region of the gamma-globin gene in unfractionated B-cell extracts.

G Superti-Furga1, A Barberis, E Schreiber, M Busslinger.   

Abstract

We have identified, by DNase I footprinting, six different factors that interact with the promoter of the human A gamma-globin gene in nuclear extracts of the B-cell line BJA-B. Among them is the vertebrate homologue of the sea-urchin CCAAT displacement protein (CDP) which footprints over the entire duplicated CCAAT region. The CCAAT-binding factor CP1, a potential activator of the gamma-globin promoter, is able to bind to its proximal recognition sequence only once it has been partially enriched and separated from CDP. The factor CDP has an apparent molecular mass of 200 kDa and differs from CP1 by its footprint pattern and competition behavior.

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Year:  1989        PMID： 2784063     DOI： 10.1016/0167-4781(89)90046-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  19 in total

1.  p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.

Authors:  Mary Truscott; Ryoko Harada; Charles Vadnais; François Robert; Alain Nepveu
Journal:  Mol Cell Biol       Date:  2008-03-17       Impact factor: 4.272

2.  Hepatomegaly in transgenic mice expressing the homeobox gene Cux-1.

Authors:  Gregory B Vanden Heuvel; Jennifer G Brantley; Neal I Alcalay; Madhulika Sharma; Gabor Kemeny; Joshua Warolin; Aric W Ledford; David M Pinson
Journal:  Mol Carcinog       Date:  2005-05       Impact factor: 4.784

3.  CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.

Authors:  S Pattison; D G Skalnik; A Roman
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

4.  Transcriptional regulation of the human KiSS1 gene.

Authors:  Johanna K Mueller; Anja Dietzel; Alejandro Lomniczi; Alberto Loche; Katrin Tefs; Wieland Kiess; Thomas Danne; Sergio R Ojeda; Sabine Heger
Journal:  Mol Cell Endocrinol       Date:  2011-06-06       Impact factor: 4.102

5.  Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network.

Authors:  Johanna K Mueller; Ines Koch; Alejandro Lomniczi; Alberto Loche; Tomke Rulfs; Juan M Castellano; Wieland Kiess; Sergio Ojeda; Sabine Heger
Journal:  Mol Cell Endocrinol       Date:  2011-12-19       Impact factor: 4.102

6.  The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase.

Authors:  Laurent Sansregret; Brigitte Goulet; Ryoko Harada; Brian Wilson; Lam Leduy; Jacques Bertoglio; Alain Nepveu
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

7.  Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.

Authors:  B Aufiero; E J Neufeld; S H Orkin
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-02       Impact factor: 11.205

8.  The deletion of the distal CCAAT box region of the A gamma-globin gene in black HPFH abolishes the binding of the erythroid specific protein NFE3 and of the CCAAT displacement protein.

Authors:  R Mantovani; G Superti-Furga; J Gilman; S Ottolenghi
Journal:  Nucleic Acids Res       Date:  1989-08-25       Impact factor: 16.971

9.  The human cut homeodomain protein represses transcription from the c-myc promoter.

Authors:  D Dufort; A Nepveu
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

10.  Cux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activator.

Authors:  Z Wang; A Goldstein; R T Zong; D Lin; E J Neufeld; R H Scheuermann; P W Tucker
Journal:  Mol Cell Biol       Date:  1999-01       Impact factor: 4.272
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