Literature DB >> 27838642

A comparative investigation of azole susceptibility in Candida isolates from vulvovaginal candidiasis and recurrent vulvovaginal candidiasis patients in Ghana.

Gloria Adjapong1, Marie Hale1, Ashley Garrill1.   

Abstract

Vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) affect millions of women and are typically treated with azoles. We know little about azole susceptibility of Candida species from VVC versus RVVC patients, and nothing about African isolates. We have investigated the susceptibility of Candida isolates from Ghana to fluconazole, itraconazole and/or voriconazole. The percentage of Candida albicans isolates showing susceptibility was significantly lower in RVVC than VVC patients. Isolates of Candida parapsilosis and Candida tropicalis showed a similar trend. For Candida glabrata there was no observed difference. The data indicate a decreased susceptibility in selected Candida species from RVVC patients.
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Entities:  

Keywords:  Candida; Ghana; azole susceptibility; recurrent vulvovaginal candidiasis; vulvovaginal candidiasis

Mesh：

Substances：

Year:  2017        PMID： 27838642     DOI： 10.1093/mmy/myw122

Source DB:  PubMed          Journal:  Med Mycol        ISSN： 1369-3786            Impact factor:   4.076


  6 in total

1.  Characterization of Candida species isolated from vulvovaginal candidiasis by MALDI-TOF with in vitro antifungal susceptibility profiles.

Authors:  Narges Aslani; Roya Kokabi; Fatemeh Moradi; Kiana Abbasi; Narges Vaseghi; Mohammad Hosein Afsarian
Journal:  Curr Med Mycol       Date:  2021-12

Review 2.  The Antibiofilm Role of Biotics Family in Vaginal Fungal Infections.

Authors:  Angela Boahen; Leslie Thian Lung Than; Yi-Linn Loke; Shu Yih Chew
Journal:  Front Microbiol       Date:  2022-05-26       Impact factor: 6.064

3.  Biofilm Formation of Candida albicans Facilitates Fungal Infiltration and Persister Cell Formation in Vaginal Candidiasis.

Authors:  Xueqing Wu; Sisi Zhang; Haiying Li; Laien Shen; Chenle Dong; Yao Sun; Huale Chen; Boyun Xu; Wenyi Zhuang; Margaret Deighton; Yue Qu
Journal:  Front Microbiol       Date:  2020-06-05       Impact factor: 5.640

4.  Distinct host immune responses in recurrent vulvovaginal candidiasis and vulvovaginal candidiasis.

Authors:  Gai Ge; Zhiya Yang; Dongmei Li; Ning Zhang; Biao Chen; Dongmei Shi
Journal:  Front Immunol       Date:  2022-07-28       Impact factor: 8.786

5.  Analysis of Biofilm-Related Genes and Antifungal Susceptibility Pattern of Vaginal Candida albicans and Non-Candida albicans Species.

Authors:  Faezeh Mohammadi; Nima Hemmat; Zahra Bajalan; Amir Javadi
Journal:  Biomed Res Int       Date:  2021-05-28       Impact factor: 3.411

6.  RAFT-Derived Polymethacrylates as a Superior Treatment for Recurrent Vulvovaginal Candidiasis by Targeting Biotic Biofilms and Persister Cells.

Authors:  Xueqing Wu; Sisi Zhang; Xinxin Xu; Laien Shen; Boyun Xu; Wenzhen Qu; Wenyi Zhuang; Katherine Locock; Margaret Deighton; Yue Qu
Journal:  Front Microbiol       Date:  2019-11-07       Impact factor: 5.640
  6 in total

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