Literature DB >> 27837527

Thin-Film Hydration Followed by Extrusion Method for Liposome Preparation.

Hongwei Zhang1.   

Abstract

One of the simplest ways to prepare liposomes in a research laboratory is the thin-film hydration method followed by extrusion. This method involves making a thin lipid film in a round-bottom flask by the removal of organic solvent. Upon the addition and agitation of the dispersion medium, heterogeneous liposomes are formed. Finally, after extrusion through polycarbonate membranes, homogeneous small liposomes are obtained.

Entities:  

Keywords:  Drug delivery; Extrusion; Liposomes; Phase transition temperature; Thin-film hydration

Mesh：

Substances：

Year:  2017        PMID： 27837527     DOI： 10.1007/978-1-4939-6591-5_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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