Literature DB >> 27837459

Endoscopic mucosal resection in elderly patients.

Stefano Pontone1, Rossella Palma2, Cristina Panetta2, Daniele Pironi2, Chiara Eberspacher2, Rita Angelini2, Paolo Pontone2, Antonio Catania2, Angelo Filippini2, Salvatore Sorrenti2.   

Abstract

BACKGROUND: Endoscopic mucosal resection (EMR) of early superficial colorectal carcinomas is nowadays accepted as the gold standard treatment for this type of neoplasia. AIM: This study aims to evaluate the efficacy and safety of mucosectomy in elderly patients considering the predictive value of submucosal infiltration.
METHODS: A retrospective study of all patients referred for EMR of sessile colorectal polyps classified IIa by the Paris classification between April 2013 and April 2015. A total of 50 patients (30 males (60 %); age range = 44-86; mean age = 67.7) were enrolled. Patients were divided in two groups considering 65 years as cutoff to individuate the elderly patients.
RESULTS: EMR was performed in 53 lesions: 39 were performed en bloc and 14 by piecemeal technique. 30 % of lesions were in the rectum; 11 % in the sigmoid colon; 15 % in the descending colon; 6 % in the transverse colon; 24 % in the ascendant colon; and 14 % in the cecum. The mean size of the resected specimens was 20 mm (range 8-80 mm). The rate of complete resection was 79.2 %, incomplete 13.2 %, not estimable 7 %. Ten patients underwent surgery because of an incomplete resection and/or histological evaluation.
CONCLUSIONS: Colon EMR is safe and effective in elderly patients. Endoscopy is still helped in the correct indication for surgery in high-risk surgical patients.

Entities:  

Keywords:  Colonoscopy; Colorectal cancer; Elderly patients; Endoscopic resection; Lifting sign; Polyp; Submucosal invasion

Mesh:

Year:  2016        PMID: 27837459     DOI: 10.1007/s40520-016-0661-z

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  2 in total

1.  Modified transverse coloplasty pouch: new reconstruction techniques after total mesorectal excision. Our experience.

Authors:  G Grimaldi; Chiara Eberspacher; A M Romani; D Merletti; A Maturo; S Pontone; D Pironi
Journal:  G Chir       Date:  2017 Nov-Dec

2.  Outcomes and adverse factors for endoscopic mucosal resection (EMR) of colorectal polyps in elderly patients.

Authors:  Thomas Skouras; Ashley Bond; Asimina Gaglia; Laura Bonnett; Meng Jiang Lim; Sanchoy Sarkar
Journal:  Frontline Gastroenterol       Date:  2020-02-25
  2 in total

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