Félix P Kuhn1, Sonia Hammoud2, Marie-Martine Lefèvre-Colau3, Serge Poiraudeau3, Antoine Feydy4. 1. Service de radiologie B, AP-HP, centre hospitalier universitaire Cochin, faculté de médecine, université Paris Descartes, 75679 Paris, France. Electronic address: Felix.Kuhn@usz.ch. 2. Service de radiologie B, AP-HP, centre hospitalier universitaire Cochin, faculté de médecine, université Paris Descartes, 75679 Paris, France. 3. Service de médecine physique and de réadaptation, AP-HP, centre hospitalier universitaire Cochin, faculté de médecine, université Paris Descartes, 75679 Paris, France; Inserm, U1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), épidémiologie clinique appliquées aux maladies ostéo-articulaires (Ecamo), université Paris Descartes, 75679 Paris, France. 4. Service de radiologie B, AP-HP, centre hospitalier universitaire Cochin, faculté de médecine, université Paris Descartes, 75679 Paris, France; Inserm, U1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), épidémiologie clinique appliquées aux maladies ostéo-articulaires (Ecamo), université Paris Descartes, 75679 Paris, France.
Abstract
OBJECTIVE: To determine the prevalence of simple and complex sacral perineural Tarlov cysts (TCs) in a cohort of children and adults. MATERIAL AND METHODS: Retrospective observational epidemiological study assessing 1100 consecutive sacral magnetic resonance (MR) studies, including 100 children and adolescents. All patients underwent 1.5T MR imaging with T1 and T2 weighted image acquisitions in sagittal and axial planes. All perineural cysts affecting the sacral nerve roots S1-S4 were quantitatively and qualitatively assessed. RESULTS: Two hundred and sixty-three sacral TCs were found in 132 adult patients (13.2%), with a female predominance (68%). None was found in children. The prevalence of TCs increased with age. The average number of cysts per patient was 2.0±1.2 with a maximum of 6 cysts in a single patient. Most of the cysts (87.5%) showed a homogenous central fluid collection and a parietal course of the nerve fibers. Complex patterns were present in 33 cysts (12.5%) within which 28 cysts showed endocystic crossing of nerve fibers and 5 cysts contained internal septations. Seventy cysts (26.6%) eroded the adjacent bone and 13 cysts (4.9%) extended to the pelvis. CONCLUSION: The prevalence of sacral TCs in our cohort corresponded to 13%, with a female predominance. Interestingly no TCs were found in children or adolescents (<18 years). In relation to the non-negligible percentage of complex cysts with internal septations, or endocystic crossing of nerve fibers, pre-interventional characterization of sacral TCs might help to choose an appropriate procedure in the treatment of rare symptomatic variants.
OBJECTIVE: To determine the prevalence of simple and complex sacral perineural Tarlov cysts (TCs) in a cohort of children and adults. MATERIAL AND METHODS: Retrospective observational epidemiological study assessing 1100 consecutive sacral magnetic resonance (MR) studies, including 100 children and adolescents. All patients underwent 1.5T MR imaging with T1 and T2 weighted image acquisitions in sagittal and axial planes. All perineural cysts affecting the sacral nerve roots S1-S4 were quantitatively and qualitatively assessed. RESULTS: Two hundred and sixty-three sacral TCs were found in 132 adult patients (13.2%), with a female predominance (68%). None was found in children. The prevalence of TCs increased with age. The average number of cysts per patient was 2.0±1.2 with a maximum of 6 cysts in a single patient. Most of the cysts (87.5%) showed a homogenous central fluid collection and a parietal course of the nerve fibers. Complex patterns were present in 33 cysts (12.5%) within which 28 cysts showed endocystic crossing of nerve fibers and 5 cysts contained internal septations. Seventy cysts (26.6%) eroded the adjacent bone and 13 cysts (4.9%) extended to the pelvis. CONCLUSION: The prevalence of sacral TCs in our cohort corresponded to 13%, with a female predominance. Interestingly no TCs were found in children or adolescents (<18 years). In relation to the non-negligible percentage of complex cysts with internal septations, or endocystic crossing of nerve fibers, pre-interventional characterization of sacral TCs might help to choose an appropriate procedure in the treatment of rare symptomatic variants.