Literature DB >> 2783447

Development and application of radioimmunoassays for interleukin-1 alpha and interleukin-1 beta.

S Poole1, A F Bristow, S Selkirk, B Rafferty.   

Abstract

Specific and sensitive radioimmunoassay (RIA) systems for human IL-1 alpha and IL-1 beta, using sheep polyclonal antisera, have been developed. The assays, which do not require prior extraction of IL-1, have been used to quantify IL-1 alpha and IL-1 beta in synovial fluid and plasma and to quantify intracellular and extracellular IL-1 alpha and IL-1 beta produced by human monocytes stimulated with endotoxin.

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Year:  1989        PMID: 2783447     DOI: 10.1016/0022-1759(89)90212-3

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  13 in total

1.  Detection of cytoplasmic IL-1 beta in peripheral blood mononuclear cells from intensive care unit (ICU) patients.

Authors:  S M Yentis; A W Rowbottom; P G Riches
Journal:  Clin Exp Immunol       Date:  1995-05       Impact factor: 4.330

Review 2.  Cytokines as mediators in the regulation of the hypothalamic-pituitary-adrenocortical function.

Authors:  J Fukata; H Imura; K Nakao
Journal:  J Endocrinol Invest       Date:  1994-02       Impact factor: 4.256

3.  An assessment of myeloid colony-forming-cell generation in liquid human bone marrow cultures: influence of accessory cells and cytokines IL-1 alpha, beta and IL-6.

Authors:  R P Gooding; P G Riches; M Y Gordon
Journal:  Int J Exp Pathol       Date:  1993-04       Impact factor: 1.925

4.  Chloroquine inhibits T cell proliferation by interfering with IL-2 production and responsiveness.

Authors:  R B Landewé; A M Miltenburg; M J Verdonk; C L Verweij; F C Breedveld; M R Daha; B A Dijkmans
Journal:  Clin Exp Immunol       Date:  1995-10       Impact factor: 4.330

5.  Interleukin-8 as a mediator of sympathetic pain.

Authors:  F Q Cunha; B B Lorenzetti; S Poole; S H Ferreira
Journal:  Br J Pharmacol       Date:  1991-11       Impact factor: 8.739

6.  The pivotal role of tumour necrosis factor alpha in the development of inflammatory hyperalgesia.

Authors:  F Q Cunha; S Poole; B B Lorenzetti; S H Ferreira
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

7.  Human cartilage is degraded by rheumatoid arthritis synovial fluid but not by recombinant cytokines in vitro.

Authors:  A P Hollander; R M Atkins; D M Eastwood; P A Dieppe; C J Elson
Journal:  Clin Exp Immunol       Date:  1991-01       Impact factor: 4.330

8.  Anti-IL-1 alpha autoantibodies in patients with rheumatic diseases and in healthy subjects.

Authors:  H Suzuki; T Ayabe; J Kamimura; H Kashiwagi
Journal:  Clin Exp Immunol       Date:  1991-09       Impact factor: 4.330

9.  Immunosuppressive activity of corticotrophin-releasing factor. Inhibition of interleukin-1 and interleukin-6 production by human mononuclear cells.

Authors:  P Hagan; S Poole; A F Bristow
Journal:  Biochem J       Date:  1992-01-01       Impact factor: 3.857

10.  Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-2, interferon-gamma (IFN-gamma), tumour necrosis factor-alpha (TNF-alpha) and IL-6 on the production of immunoreactive IL-1 and TNF-alpha by human monocytes.

Authors:  V A Danis; G M Franic; D A Rathjen; P M Brooks
Journal:  Clin Exp Immunol       Date:  1991-07       Impact factor: 4.330

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