Literature DB >> 27834398

Cancer nanomedicine: progress, challenges and opportunities.

Jinjun Shi1, Philip W Kantoff2, Richard Wooster3, Omid C Farokhzad1,4.   

Abstract

The intrinsic limits of conventional cancer therapies prompted the development and application of various nanotechnologies for more effective and safer cancer treatment, herein referred to as cancer nanomedicine. Considerable technological success has been achieved in this field, but the main obstacles to nanomedicine becoming a new paradigm in cancer therapy stem from the complexities and heterogeneity of tumour biology, an incomplete understanding of nano-bio interactions and the challenges regarding chemistry, manufacturing and controls required for clinical translation and commercialization. This Review highlights the progress, challenges and opportunities in cancer nanomedicine and discusses novel engineering approaches that capitalize on our growing understanding of tumour biology and nano-bio interactions to develop more effective nanotherapeutics for cancer patients.

Entities:  

Mesh：

Year:  2016        PMID： 27834398      PMCID： PMC5575742          DOI： 10.1038/nrc.2016.108

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  240 in total

1.  Mitochondriotropic liposomes.

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Journal:  J Liposome Res       Date:  2005       Impact factor: 3.648

Review 2.  Microenvironmental regulation of tumor progression and metastasis.

Authors:  Daniela F Quail; Johanna A Joyce
Journal:  Nat Med       Date:  2013-11       Impact factor: 53.440

3.  Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors.

Authors:  Jaehong Key; Anna Lisa Palange; Francesco Gentile; Santosh Aryal; Cinzia Stigliano; Daniele Di Mascolo; Enrica De Rosa; Minjung Cho; Yeonju Lee; Jaykrishna Singh; Paolo Decuzzi
Journal:  ACS Nano       Date:  2015-11-05       Impact factor: 15.881

4.  Antibody targeting of liposomes: cell specificity obtained by conjugation of F(ab')2 to vesicle surface.

Authors:  T D Heath; R T Fraley; D Papahdjopoulos
Journal:  Science       Date:  1980-10-31       Impact factor: 47.728

5.  Engineered nanomedicine for myeloma and bone microenvironment targeting.

Authors:  Archana Swami; Michaela R Reagan; Pamela Basto; Yuji Mishima; Nazila Kamaly; Siobhan Glavey; Sufeng Zhang; Michele Moschetta; Dushanth Seevaratnam; Yong Zhang; Jinhe Liu; Masoumeh Memarzadeh; Jun Wu; Salomon Manier; Jinjun Shi; Nicolas Bertrand; Zhi Ning Lu; Kenichi Nagano; Roland Baron; Antonio Sacco; Aldo M Roccaro; Omid C Farokhzad; Irene M Ghobrial
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-30       Impact factor: 11.205

6.  Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics.

Authors:  William B Liechty; Mary Caldorera-Moore; Margaret A Phillips; Cody Schoener; Nicholas A Peppas
Journal:  J Control Release       Date:  2011-06-14       Impact factor: 9.776

7.  Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions.

Authors:  Alessandro Parodi; Nicoletta Quattrocchi; Anne L van de Ven; Ciro Chiappini; Michael Evangelopoulos; Jonathan O Martinez; Brandon S Brown; Sm Z Khaled; Iman K Yazdi; Maria Vittoria Enzo; Lucas Isenhart; Mauro Ferrari; Ennio Tasciotti
Journal:  Nat Nanotechnol       Date:  2012-12-16       Impact factor: 39.213

8.  Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface.

Authors:  Anna Salvati; Andrzej S Pitek; Marco P Monopoli; Kanlaya Prapainop; Francesca Baldelli Bombelli; Delyan R Hristov; Philip M Kelly; Christoffer Åberg; Eugene Mahon; Kenneth A Dawson
Journal:  Nat Nanotechnol       Date:  2013-01-20       Impact factor: 39.213

Review 9.  Vascular targeting of nanocarriers: perplexing aspects of the seemingly straightforward paradigm.

Authors:  Melissa Howard; Blaine J Zern; Aaron C Anselmo; Vladimir V Shuvaev; Samir Mitragotri; Vladimir Muzykantov
Journal:  ACS Nano       Date:  2014-05-07       Impact factor: 15.881

10.  Tumor-associated macrophages are predominant carriers of cyclodextrin-based nanoparticles into gliomas.

Authors:  Darya Alizadeh; Leying Zhang; Jungyeon Hwang; Thomas Schluep; Behnam Badie
Journal:  Nanomedicine       Date:  2009-11-05       Impact factor: 5.307
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  817 in total

1.  An effective vaginal gel to deliver CRISPR/Cas9 system encapsulated in poly (β-amino ester) nanoparticles for vaginal gene therapy.

Authors:  Gang Niu; Zhuang Jin; Chong Zhang; Dan He; Xueqin Gao; Chenming Zou; Wei Zhang; Jiahui Ding; Bhudev C Das; Konstantin Severinov; Inga Isabel Hitzeroth; Priya Ranjan Debata; Xin Ma; Xun Tian; Qinglei Gao; Jun Wu; Zeshan You; Rui Tian; Zifeng Cui; Weiwen Fan; Weiling Xie; Zhaoyue Huang; Chen Cao; Wei Xu; Hongxian Xie; Hongyan Xu; Xiongzhi Tang; Yan Wang; Zhiying Yu; Hui Han; Songwei Tan; Shuqin Chen; Zheng Hu
Journal:  EBioMedicine       Date:  2020-07-22       Impact factor: 8.143

2.  Biohybrid Nanosystems for Cancer Treatment: Merging the Best of Two Worlds.

Authors:  Flavia Fontana; Raquél Bartolo; Hélder A Santos
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

3.  Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin.

Authors:  Hye-Yeong Kim; Ran Li; Thomas S C Ng; Gabriel Courties; Christopher Blake Rodell; Mark Prytyskach; Rainer H Kohler; Mikael J Pittet; Matthias Nahrendorf; Ralph Weissleder; Miles A Miller
Journal:  ACS Nano       Date:  2018-12-11       Impact factor: 15.881

4.  Drug loading augmentation in polymeric nanoparticles using a coaxial turbulent jet mixer: Yong investigator perspective.

Authors:  Jong-Min Lim; Truong Cai; Stefan Mandaric; Sunandini Chopra; Hyeonwoo Han; Seokkyu Jang; Won Il Choi; Robert Langer; Omid C Farokhzad; Rohit Karnik
Journal:  J Colloid Interface Sci       Date:  2018-11-10       Impact factor: 8.128

5.  Gadolinium-Encapsulated Graphene Carbon Nanotheranostics for Imaging-Guided Photodynamic Therapy.

Authors:  Hongmin Chen; Yuwei Qiu; Dandan Ding; Huirong Lin; Wenjing Sun; Geoffrey D Wang; Weicheng Huang; Weizhong Zhang; Daye Lee; Gang Liu; Jin Xie; Xiaoyuan Chen
Journal:  Adv Mater       Date:  2018-07-23       Impact factor: 30.849

6.  Polyester Nanoparticle Encapsulation Mitigates Paclitaxel-Induced Peripheral Neuropathy.

Authors:  R Ganugula; M Deng; M Arora; H-L Pan; M N V Ravi Kumar
Journal:  ACS Chem Neurosci       Date:  2019-01-17       Impact factor: 4.418

7.  Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose.

Authors:  Wen Yang; Hanitrarimalala Veroniaina; Xiaole Qi; Pengyu Chen; Feng Li; Pu Chun Ke
Journal:  Adv Ther (Weinh)       Date:  2019-10-16

8.  Simulation of Stimuli-Responsive and Stoichiometrically Controlled Release Rate of Doxorubicin from Liposomes in Tumor Interstitial Fluid.

Authors:  Eiichi Yamamoto; Kenji Hyodo; Takuya Suzuki; Hiroshi Ishihara; Hiroshi Kikuchi; Masaru Kato
Journal:  Pharm Res       Date:  2018-03-19       Impact factor: 4.200

9.  Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy.

Authors:  Xiang Ling; Jiasheng Tu; Junqing Wang; Aram Shajii; Na Kong; Chan Feng; Ye Zhang; Mikyung Yu; Tian Xie; Zameer Bharwani; Bader M Aljaeid; Bingyang Shi; Wei Tao; Omid C Farokhzad
Journal:  ACS Nano       Date:  2018-12-04       Impact factor: 15.881

10.  Cross-Linked Aptamer-Lipid Micelles for Excellent Stability and Specificity in Target-Cell Recognition.

Authors:  Xiaowei Li; C Adrian Figg; Ruowen Wang; Ying Jiang; Yifan Lyu; Hao Sun; Yuan Liu; Yanyue Wang; I-Ting Teng; Weijia Hou; Ren Cai; Cheng Cui; Long Li; Xiaoshu Pan; Brent S Sumerlin; Weihong Tan
Journal:  Angew Chem Int Ed Engl       Date:  2018-08-06       Impact factor: 15.336
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