Victoria K Shanmugam1. 1. Division of Rheumatology, The George Washington University, School of Medicine and Health Sciences, 701 Ross Hall, 2300 Eye Street, NW, Washington, DC 20037.
Abstract
PURPOSE: Autoimmune diseases are a common cause of delayed wound healing and should be considered in patients with chronic wounds who do not respond to local wound care or who fail skin grafting in the absence of infection. RECENT FINDINGS: Epidemiologic studies have shown that, of patients with chronic wounds evaluated in specialized wound healing clinics, 20-23% have autoimmune etiologies for their wounds including vasculitis, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, pyoderma gangrenosum and other autoimmune diseases. SUMMARY: In this article autoimmune diseases known to be associated with chronic wounds and delayed wound healing are reviewed and the importance of a multidisciplinary approach for patients with chronic wounds, with involvement of rheumatology and dermatology is highlighted. This approach allows for investigation of underlying systemic disease and improves clinical outcomes for many of these challenging patients.
PURPOSE:Autoimmune diseases are a common cause of delayed wound healing and should be considered in patients with chronic wounds who do not respond to local wound care or who fail skin grafting in the absence of infection. RECENT FINDINGS: Epidemiologic studies have shown that, of patients with chronic wounds evaluated in specialized wound healing clinics, 20-23% have autoimmune etiologies for their wounds including vasculitis, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, pyoderma gangrenosum and other autoimmune diseases. SUMMARY: In this article autoimmune diseases known to be associated with chronic wounds and delayed wound healing are reviewed and the importance of a multidisciplinary approach for patients with chronic wounds, with involvement of rheumatology and dermatology is highlighted. This approach allows for investigation of underlying systemic disease and improves clinical outcomes for many of these challenging patients.
Authors: Armando De Virgilio; Antonio Greco; Giuseppe Magliulo; Andrea Gallo; Giovanni Ruoppolo; Michela Conte; Salvatore Martellucci; Marco de Vincentiis Journal: Autoimmun Rev Date: 2016-02-13 Impact factor: 9.754
Authors: Victoria K Shanmugam; Sean McNish; Joanna Duncan; Brandy Root; Elena Tassi; Anton Wellstein; Bhaskar Kallakury; Christopher E Attinger Journal: Int Wound J Date: 2013-09-13 Impact factor: 3.315
Authors: Roger H Weenig; Lindsay D Sewell; Mark D P Davis; James T McCarthy; Mark R Pittelkow Journal: J Am Acad Dermatol Date: 2006-12-01 Impact factor: 11.527
Authors: Victoria K Shanmugam; Stephen J Fernandez; Karen Kim Evans; Sean McNish; Anirban N Banerjee; Kara S Couch; Mihriye Mete; Nawar Shara Journal: Wound Repair Regen Date: 2015 Mar-Apr Impact factor: 3.617
Authors: Susan Manzi; Jorge Sánchez-Guerrero; Joan T Merrill; Richard Furie; Dafna Gladman; Sandra V Navarra; Ellen M Ginzler; David P D'Cruz; Andrea Doria; Simon Cooper; Z John Zhong; Douglas Hough; William Freimuth; Michelle A Petri Journal: Ann Rheum Dis Date: 2012-05-01 Impact factor: 19.103