Literature DB >> 27833347

Treatment of Keratocystic Odontogenic Tumours: A Prospective Study of 30 Cases.

Ashish Gupta1, Pankaj Bansal1, Rahul Sharma1, Sneha D Sharma1.   

Abstract

AIM: This prospective study aimed at presenting different treatment modalities and its association with the recurrence rate of KCOT. MATERIAL AND
METHOD: The study was conducted on 30 patients diagnosed with KCOT between March 2009 and 2012. The patients were followed up for a period of at least 1 year. The clinical, radiographic and demographic data were recorded and four different treatment modalities were followed to assess the recurrence of the tumour.
RESULTS: In the study, KCOT showed male predominance with a male: female ratio of 23:7. Of the total cases, 26 (86.67 %) patients had parakeratinised KCOT and the rest 4 (13.3 %) patients had orthokeratnised KCOT. Nine (30 %) patients were reported with recurrence of the tumour within 1-2 years of surgery-all these patients had parakeratinised cyst. Recurrence was observed in four (50 %) out of eight cases of marsupialisation and four (44.44 %) out of nine cases of treatment using the enucleation process. No recurrence was seen in patients treated with resection; however only one out of three patients treated with enucleation, followed by fixation with Carnoy's solution showed signs of recurrence. The histopathological examination determined the aggressive nature of KCOT and its association with the recurrence rate as well. The findings of our study indicate that more aggressive treatment can aid in reducing the chances of recurrence.

Entities:  

Keywords:  KCOT; Orthokeratinized; Parakeratinized; Recurrence; Treatment modalities

Year:  2016        PMID: 27833347      PMCID: PMC5083689          DOI: 10.1007/s12663-015-0875-1

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  20 in total

Review 1.  Systematic review of the treatment and prognosis of the odontogenic keratocyst.

Authors:  N Blanas; B Freund; M Schwartz; I M Furst
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2000-11

2.  Treatment of keratocysts: the case for decompression and marsupialization.

Authors:  M Anthony Pogrel
Journal:  J Oral Maxillofac Surg       Date:  2005-11       Impact factor: 1.895

3.  Odontogenic keratocyst of the maxilla: a case report.

Authors:  V J Lund
Journal:  Br J Oral Maxillofac Surg       Date:  1985-06       Impact factor: 1.651

4.  Odontogenic keratocysts: a clinical, radiographic, and histopathologic study.

Authors:  J I Haring; M L Van Dis
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1988-07

5.  Clinicopathologic study of odontogenic keratocysts in Singapore and Malaysia.

Authors:  W C Ngeow; R B Zain; J F Yeo; W L Chai
Journal:  J Oral Sci       Date:  2000-03       Impact factor: 1.556

6.  Collagenolytic activity in keratocysts.

Authors:  R B Donoff; E Harper; W C Guralnick
Journal:  J Oral Surg       Date:  1972-12

7.  Lactoferrin in aspirates of odontogenic cyst fluid.

Authors:  A J Smith; J B Matthews; G I Mason; R M Browne
Journal:  J Clin Pathol       Date:  1988-10       Impact factor: 3.411

8.  A retrospective review of treatment of the odontogenic keratocyst.

Authors:  Teresa A Morgan; Christopher C Burton; Fang Qian
Journal:  J Oral Maxillofac Surg       Date:  2005-05       Impact factor: 1.895

Review 9.  Keratocystic odontogenic tumour: systematic review.

Authors:  D S MacDonald-Jankowski
Journal:  Dentomaxillofac Radiol       Date:  2011-01       Impact factor: 2.419

10.  Marsupialization inhibits interleukin-1alpha expression and epithelial cell proliferation in odontogenic keratocysts.

Authors:  Tomohiro Ninomiya; Yasutaka Kubota; Takehiko Koji; Kanemitsu Shirasuna
Journal:  J Oral Pathol Med       Date:  2002-10       Impact factor: 4.253

View more
  2 in total

1.  Recurrence of nonsyndromic odontogenic keratocyst after marsupialization and delayed enucleation vs. enucleation alone: a systematic review and meta-analysis.

Authors:  Yuri Slusarenko da Silva; Paul J W Stoelinga; Maria da Graça Naclério-Homem
Journal:  Oral Maxillofac Surg       Date:  2018-11-29

2.  Multidisciplinary oral rehabilitation of an adolescent suffering from juvenile Gorlin-Goltz syndrome - a case report.

Authors:  Manfred Nilius; Jürgen Kohlhase; Johann Lorenzen; Günter Lauer; Matthias C Schulz
Journal:  Head Face Med       Date:  2019-02-08       Impact factor: 2.151

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.