Literature DB >> 27833337

Eventuality of Dexamethasone Injected Intra-massetrically on Post Operative Sequel Following the Surgical Extraction of Impacted Mandibular Third Molars: A Prospective Study.

G D Nandini1.   

Abstract

OBJECTIVE: The objective of the study was to compare the efficacy of dexamethasone given intra-massetrically via intra buccal approach on postoperative sequele after surgical extraction of impacted mandibular third molars.
METHODOLOGY: Twenty patients, each of who required surgical extraction of a single impacted mandibular third molar under local anesthesia, were randomly set apart to one of the two groups of ten each. The experimental group received dexamethasone 8 mg injected to the masseter muscle intra buccally and the control group did not receive any steroid. Facial swelling and maximal inter-incisal distance were measured by an independent examiner preoperatively, and at 4th h, on the day of surgery, 2 and 7 postoperative days. Pain was measured from the patient's response to a visual analogue scale.
RESULTS: Patients were of the age range 18-40 years. Dexamethasone group showed significant reduction in swelling and pain compared with the control group at all intervals. Dexamethasone injected into the masseter muscle via intra buccal approach resulted in significantly less trismus than control on day one postoperatively.
CONCLUSION: Dexamethasone 8 mg given intra-massetrically through intra buccal approach is an effective way of minimizing swelling, trismus, and pain following surgical extraction of impacted mandibular third molars. It offers a simple, safe, painless, non-invasive and cost-effective treatment.

Entities:  

Keywords:  Dexamethasone; Impacted third molar; Intra-massetric

Year:  2015        PMID: 27833337      PMCID: PMC5083682          DOI: 10.1007/s12663-015-0847-5

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  17 in total

1.  Efficacy of methylprednisolone injected into the masseter muscle following the surgical extraction of impacted lower third molars.

Authors:  E Vegas-Bustamante; J Micó-Llorens; J Gargallo-Albiol; M Satorres-Nieto; L Berini-Aytés; C Gay-Escoda
Journal:  Int J Oral Maxillofac Surg       Date:  2008-03-04       Impact factor: 2.789

Review 2.  Corticosteroids reduce postoperative morbidity after third molar surgery: a systematic review and meta-analysis.

Authors:  Michael R Markiewicz; Mark F Brady; Eric L Ding; Thomas B Dodson
Journal:  J Oral Maxillofac Surg       Date:  2008-09       Impact factor: 1.895

3.  Glucocorticoids suppress levels of immunoreactive bradykinin in inflamed tissue as evaluated by microdialysis probes.

Authors:  K M Hargreaves; A Costello
Journal:  Clin Pharmacol Ther       Date:  1990-08       Impact factor: 6.875

4.  Effect of methylprednisolone on complications after removal of impacted mandibular third molars.

Authors:  H Bystedt; A Nordenram
Journal:  Swed Dent J       Date:  1985

5.  An uncommon adverse effect following bolus administration of intravenous dexamethasone.

Authors:  D Andrews; V J Grunau
Journal:  J Can Dent Assoc       Date:  1986-04       Impact factor: 1.316

Review 6.  Glucocorticosteroids in dentistry.

Authors:  S L Bahn
Journal:  J Am Dent Assoc       Date:  1982-09       Impact factor: 3.634

7.  Determination of the anti-inflammatory effects of methylprednisolone on the sequelae of third molar surgery.

Authors:  E Esen; F Taşar; O Akhan
Journal:  J Oral Maxillofac Surg       Date:  1999-10       Impact factor: 1.895

8.  Dexamethasone suppresses peripheral prostanoid levels without analgesia in a clinical model of acute inflammation.

Authors:  Raymond A Dionne; Sharon M Gordon; Janet Rowan; Allison Kent; Jaime S Brahim
Journal:  J Oral Maxillofac Surg       Date:  2003-09       Impact factor: 1.895

9.  Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.

Authors:  Yakup UStün; Ozgür Erdogan; Emin Esen; Ebru Deniz Karsli
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2003-11

10.  The use of intraoral dexamethasone after extraction of mandibular third molars.

Authors:  E J Messer; J J Keller
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1975-11
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  2 in total

1.  Morbidity following transcrestal and lateral sinus floor elevation: A randomized trial.

Authors:  Roberto Farina; Giovanni Franceschetti; Domenico Travaglini; Ugo Consolo; Luigi Minenna; Gian Pietro Schincaglia; Orio Riccardi; Alberto Bandieri; Elisa Maietti; Leonardo Trombelli
Journal:  J Clin Periodontol       Date:  2018-08-03       Impact factor: 8.728

2.  Efficacy of Submucosal Injection of Chymotrypsin, Oral Serratiopeptidase or Oral Dexamethasone in Reducing Postoperative Complications Following Impacted Lower Third Molar Surgery: A Prospective, Randomized, Double-Blind, Controlled Clinical Trial.

Authors:  Essam Ahmed Al-Moraissi; Elham Aziz Al-Zendani; Abeer Mohammed Al-Selwi
Journal:  Front Oral Health       Date:  2020-12-08
  2 in total

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