| Literature DB >> 27832545 |
Rebecca S DeVaux1, Marcy Kuentzel2, Jason Herschkowitz2, Sridar V Chittur3,4.
Abstract
Understanding differential isoform expression is critical to mechanistically illuminate the biology underlying both normal development and disease states. High-throughput expression profiling analysis of splice variants has thus far been limited by sample requirements and an appropriate platform for quantitation and analysis. Here we describe Affymetrix GeneChip Human Transcriptome Array 2.0, which is employed for comprehensive examination of all known transcript isoforms.Entities:
Keywords: Alternative splicing; Exon splicing; Expression profiling; Gene regulation; Microarray
Mesh:
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Year: 2017 PMID: 27832545 DOI: 10.1007/978-1-4939-6518-2_18
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745