Literature DB >> 27832545

Determination of Alternate Splicing Events Using Transcriptome Arrays.

Rebecca S DeVaux1, Marcy Kuentzel2, Jason Herschkowitz2, Sridar V Chittur3,4.   

Abstract

Understanding differential isoform expression is critical to mechanistically illuminate the biology underlying both normal development and disease states. High-throughput expression profiling analysis of splice variants has thus far been limited by sample requirements and an appropriate platform for quantitation and analysis. Here we describe Affymetrix GeneChip Human Transcriptome Array 2.0, which is employed for comprehensive examination of all known transcript isoforms.

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Keywords:  Alternative splicing; Exon splicing; Expression profiling; Gene regulation; Microarray

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Year:  2017        PMID: 27832545     DOI: 10.1007/978-1-4939-6518-2_18

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  1 in total

1.  PRKCSH Alternative Splicing Involves in Silica-Induced Expression of Epithelial-Mesenchymal Transition Markers and Cell Proliferation.

Authors:  Ruixue Huang; Xiaodan Liu; He Li; Huacheng Ning; Ping-Kun Zhou
Journal:  Dose Response       Date:  2020-05-08       Impact factor: 2.658

  1 in total

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