Literature DB >> 27832506

Production and application of menaquinone-7 (vitamin K2): a new perspective.

Ehsan Mahdinia1, Ali Demirci1, Aydin Berenjian2.   

Abstract

Menaquinone-7, a highly valuable member of the vitamin K series, has significant effects on preventing osteoporosis and cardiovascular disease besides its positive effects on blood coagulation. In this review, chemical and biological aspects of menaquinone-7 are briefly summarized followed by a critical review on upstream and downstream processing developments for its production and recovery, including solid versus liquid fermentations, static versus agitated fermentations and online versus post-production recovery. Latest research outcomes for improving industrial scale production of menaquinone-7 are summarized and recommendations are given for areas of future research.

Entities:  

Keywords:  Fermentation; Menaquinone; Nutritional benefits; Production; Separation; Vitamin K

Mesh：

Substances：

Year:  2016        PMID： 27832506     DOI： 10.1007/s11274-016-2169-2

Source DB:  PubMed          Journal:  World J Microbiol Biotechnol        ISSN： 0959-3993            Impact factor:   3.312


  31 in total

Review 1.  Current and future trends for biofilm reactors for fermentation processes.

Authors:  Duygu Ercan; Ali Demirci
Journal:  Crit Rev Biotechnol       Date:  2013-08-06       Impact factor: 8.429

2.  Phylloquinone (vitamin K(1) ) biosynthesis in plants: two peroxisomal thioesterases of Lactobacillales origin hydrolyze 1,4-dihydroxy-2-naphthoyl-CoA.

Authors:  Joshua R Widhalm; Anne-Lise Ducluzeau; Nicole E Buller; Christian G Elowsky; Laura J Olsen; Gilles J C Basset
Journal:  Plant J       Date:  2012-06-19       Impact factor: 6.417

3.  Production of menaquinone (vitamin K2)-7 by Bacillus subtilis.

Authors:  T Sato; Y Yamada; Y Ohtani; N Mitsui; H Murasawa; S Araki
Journal:  J Biosci Bioeng       Date:  2001       Impact factor: 2.894

4.  Efficient media for high menaquinone-7 production: response surface methodology approach.

Authors:  Aydin Berenjian; Raja Mahanama; Andrea Talbot; Ray Biffin; Hubert Regtop; Peter Valtchev; John Kavanagh; Fariba Dehghani
Journal:  N Biotechnol       Date:  2011-08-03       Impact factor: 5.079

Review 5.  Vitamin K series: current status and future prospects.

Authors:  Aydin Berenjian; Raja Mahanama; John Kavanagh; Fariba Dehghani
Journal:  Crit Rev Biotechnol       Date:  2013-09-18       Impact factor: 8.429

Review 6.  Metabolism and cell biology of vitamin K.

Authors:  Martin J Shearer; Paul Newman
Journal:  Thromb Haemost       Date:  2008-10       Impact factor: 5.249

7.  Effect of biofilm formation by Bacillus subtilis natto on menaquinone-7 biosynthesis.

Authors:  Aydin Berenjian; Natalie Li-Cheng Chan; Raja Mahanama; Andrea Talbot; Hubert Regtop; John Kavanagh; Fariba Dehghani
Journal:  Mol Biotechnol       Date:  2013-06       Impact factor: 2.695

8.  Magnetic immobilization of Bacillus subtilis natto cells for menaquinone-7 fermentation.

Authors:  Alireza Ebrahiminezhad; Vikas Varma; Shuyi Yang; Aydin Berenjian
Journal:  Appl Microbiol Biotechnol       Date:  2015-09-24       Impact factor: 4.813

Review 9.  Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis.

Authors:  Masayoshi Yamaguchi
Journal:  Yakugaku Zasshi       Date:  2006-11       Impact factor: 0.302

10.  Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7.

Authors:  Leon J Schurgers; Kirsten J F Teunissen; Karly Hamulyák; Marjo H J Knapen; Hogne Vik; Cees Vermeer
Journal:  Blood       Date:  2006-12-07       Impact factor: 22.113
View more
  9 in total

Review 1.  Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities.

Authors:  Nikita Jadhav; Saiprasad Ajgaonkar; Praful Saha; Pranay Gurav; Amitkumar Pandey; Vivek Basudkar; Yash Gada; Sangita Panda; Shashank Jadhav; Dilip Mehta; Sujit Nair
Journal:  Front Pharmacol       Date:  2022-06-14       Impact factor: 5.988

2.  Evaluation of the antitumor effects of vitamin K2 (menaquinone-7) nanoemulsions modified with sialic acid-cholesterol conjugate.

Authors:  Jia Shi; Songlei Zhou; Le Kang; Hu Ling; Jiepeng Chen; Lili Duan; Yanzhi Song; Yihui Deng
Journal:  Drug Deliv Transl Res       Date:  2018-02       Impact factor: 4.617

3.  Effects of microgravity on osteoblast mitochondria: a proteomic and metabolomics profile.

Authors:  Anna Michaletti; Magda Gioia; Umberto Tarantino; Lello Zolla
Journal:  Sci Rep       Date:  2017-11-13       Impact factor: 4.379

Review 4.  The Medical Benefits of Vitamin K2 on Calcium-Related Disorders.

Authors:  Zeyad Khalil; Benyamin Alam; Amir Reza Akbari; Harbans Sharma
Journal:  Nutrients       Date:  2021-02-21       Impact factor: 5.717

5.  Effects of Alkali Stress on the Growth and Menaquinone-7 Metabolism of Bacillus subtilis natto.

Authors:  Xiaoqian Chen; Chao Shang; Huimin Zhang; Cuicui Sun; Guofang Zhang; Libo Liu; Chun Li; Aili Li; Peng Du
Journal:  Front Microbiol       Date:  2022-04-28       Impact factor: 5.640

6.  Supercritical Fluid Chromatography with Photodiode Array Detection in the Determination of Fat-Soluble Vitamins in Hemp Seed Oil and Waste Fish Oil.

Authors:  Katarzyna Tyśkiewicz; Roman Gieysztor; Izabela Maziarczyk; Paweł Hodurek; Edward Rój; Krystyna Skalicka-Woźniak
Journal:  Molecules       Date:  2018-05-10       Impact factor: 4.411

7.  How menaquinone-7 deficiency influences mortality and morbidity among COVID-19 patients.

Authors:  Aydin Berenjian; Zahra Sarabadani
Journal:  Biocatal Agric Biotechnol       Date:  2020-09-16

Review 8.  Synthesis of Naphthoquinone Derivatives: Menaquinones, Lipoquinones and Other Vitamin K Derivatives.

Authors:  Margaret Braasch-Turi; Debbie C Crans
Journal:  Molecules       Date:  2020-09-29       Impact factor: 4.411

Review 9.  Production of Vitamin K by Wild-Type and Engineered Microorganisms.

Authors:  Min-Ji Kang; Kwang-Rim Baek; Ye-Rim Lee; Geun-Hyung Kim; Seung-Oh Seo
Journal:  Microorganisms       Date:  2022-03-03
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.