Literature DB >> 27832469

Management of concomitant hyperparathyroidism and thyroid diseases in the elderly patients: a retrospective cohort study.

Alessandra Panarese1, Vito D'Andrea2, Stefano Pontone2, Pasqualino Favoriti2, Daniele Pironi2, Stefano Arcieri2, Angelo Filippini2, Salvatore Sorrenti2.   

Abstract

BACKGROUND: Thyroid disease and hyperparathyroidism are the most common endocrine disorders. The incidence of thyroid disease in patients with hyperparathyroidism ranges in the different series from 17 to 84%, and thyroid cancer occurs with an incidence ranging from 2 to 15%. AIM: The aim of our study was to analyze the management of elderly patients with concomitant thyroid and parathyroid disease in order to define the best surgical therapeutic strategy and avoid reoperations associated with a higher risk of complications.
METHODS: All consecutive patients (64 patients, age range 60-75 years), undergoing surgery for hyperparathyroidism, from January 2011 to June 2014, were retrospectively evaluated. Enrolled patients were divided into two study groups of patients affected by hyperparathyroidism with or without a concomitant thyroid disease.
RESULTS: Out of 64 patients enrolled in our study (24 men, age range 60-75 years), affected by hyperparathyroidism, 34 had an associated thyroid disease and were treated with total thyroidectomy and parathyroidectomy. The group, who underwent parathyroidectomy associated with thyroidectomy, had no greater complications than the group receiving only parathyroidectomy.
CONCLUSIONS: Thyroid disease must be excluded in patients affected by hyperparathyroidism. It is difficult to determine whether hyperparathyroidism can be considered a risk factor for thyroid disease, but an accurate preoperative study is essential for a surgery able to treat both thyroid and parathyroid disease. In this way, we avoid the elderly patient, with associated morbidity and increased surgical risk, to undergo a reoperation for thyroid disease, burdened with major complications.

Entities:  

Keywords:  Hyperparathyroidism; Parathyroidectomy; Thyroid disease; Thyroidectomy

Mesh:

Year:  2016        PMID: 27832469     DOI: 10.1007/s40520-016-0665-8

Source DB:  PubMed          Journal:  Aging Clin Exp Res        ISSN: 1594-0667            Impact factor:   3.636


  2 in total

1.  Intraoperative parathyroid hormone (PTH) testing in patients with primary hyperparathyroidism and PTH levels in the normal range.

Authors:  Fabio Medas; Enrico Erdas; Giulia Loi; Francesco Podda; Lucia Barca; Giuseppe Pisano; Pietro Giorgio Calò
Journal:  BMC Surg       Date:  2019-04-24       Impact factor: 2.102

2.  Surgical Approach to Primary Hyperparathyroidism in Patients with Concomitant Thyroid Diseases: A Retrospective Single Center Study.

Authors:  Elena Castellano; Paolo Benso; Roberto Attanasio; Alberto Boriano; Corrado Lauro; Giorgio Borretta; Felice Borghi
Journal:  Int J Endocrinol       Date:  2020-02-22       Impact factor: 3.257

  2 in total

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