| Literature DB >> 27829558 |
Mina Mehrzad-Samarin1, Farnoush Faridbod2, Amin Shiralizadeh Dezfuli1, Mohammad Reza Ganjali1.
Abstract
A novel optical nanosensor for detection of Metronidazole in biological samples was reported. Graphene quantum dots embedded silica molecular imprinted polymer (GQDs-embedded SMIP) was synthesized and used as a selective fluorescent probe for Metronidazole detection. The new synthesized GQDs-embedded SMIP showed strong fluorescent emission at 450nm excited at 365nm which quenched in presence of Metronidazole as a template molecule.. The quenching was proportional to the concentration of Metronidazole in a linear range of at least 0.2μM to 15μM. The limit of detection for metronidazole determination was obtained 0.15μM. The nanosensor successfully worked in plasma matrixes.Entities:
Keywords: Fluorescence detection; Graphene quantum dots; Inorganic silica polymer; Metronidazole; Molecularly imprinted polymer; Nanosensor
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Year: 2016 PMID: 27829558 DOI: 10.1016/j.bios.2016.10.047
Source DB: PubMed Journal: Biosens Bioelectron ISSN: 0956-5663 Impact factor: 10.618