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Literature DB >> 2782651

Ketamine does not trigger malignant hyperthermia in susceptible swine.

Abstract

The use of ketamine in individuals susceptible to malignant hyperthermia (MH) is controversial. We describe our experience with ketamine used for induction and/or maintenance of anesthesia in our herd of swine inbred for susceptibility to MH. A total of 76 MH-susceptible swine were given a total of 112 general anesthetics using ketamine as the induction drug. In 34 of these anesthetics, anesthesia was also maintained with ketamine. Signs of MH did not develop in response to ketamine in any of the pigs.

Entities: Chemical Disease Species

Mesh：

Substances：
Ketamine

Year: 1989 PMID： 2782651

Source DB: PubMed Journal: Anesth Analg ISSN： 0003-2999 Impact factor: 5.108

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Cited

6 in total

1. Ketamine-midazolam anesthesia for an infant with arthrogryposis multiplex congenita: a case with decreased myocardial contractility.

Authors: H Volkan Acar; Ozgün Cuvaş; Ayşegül Ceyhan; Fatih Yücel; Bayazit Dikmen
Journal: J Anesth Date: 2011-07-08 Impact factor: 2.078

Ketamine does not trigger malignant hyperthermia in susceptible swine.

1. Ketamine-midazolam anesthesia for an infant with arthrogryposis multiplex congenita: a case with decreased myocardial contractility.

Review 2. Ketamine: a review of its pharmacologic properties and use in ambulatory anesthesia.

3. Anterior mediastinal mass in a patient susceptible to malignant hyperthermia.

4. Effects of ketamine, thiopental sodium and propofol on muscle contractures in rat diaphragm in vitro.

5. A case of malignant hyperthermia during anesthesia induction with sevoflurane -A case report-.

Review 6. Advantages of ketamine in pediatric anesthesia.