Yukihiko Ueda1, Shugo Suwazono2, Sino Maedo3, Itsuro Higuchi4. 1. Okinawa International University, Ginowan, Ginowan-shi, Okinawa, Japan. Electronic address: y.ueda@okiu.ac.jp. 2. National Hospital Organization Okinawa National Hospital, Ganeko, Ginowan-shi, Okinawa, Japan. 3. Okinawa International University, Ginowan, Ginowan-shi, Okinawa, Japan. 4. School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima-shi, Kagoshima, Japan.
Abstract
BACKGROUND: Several studies have examined intellectual functioning of boys with duchenne muscular dystrophy (DMD). However, little is known about the remaining cognitive weaknesses in adults with DMD. OBJECTIVE: The purpose of this study was to investigate the profile of cognitive functioning that is characteristics of adults with DMD. METHODS: Twenty-four subscales from the Wechsler Adult Intelligence Scale III (WAIS-III), the Clinical Assessment for Attention (CAT), and the Wechsler Memory Scale Revised (WMS-R) were used to assess participants with DMD (N=15; mean age=30.4years). RESULTS: Scores for Picture Completion, Arithmetic, Matrix Reasoning, Symbol Search, Letter-Number Sequencing, and Digit Span of the WAIS-III; all CAT scores, and Logical Memory and Delayed Logical Memory from the WMS-R were significantly deficient in adults with DMD in comparison to the normal population. CONCLUSION: The ability to sequentially process auditory and visual information remains impaired in adults with DMD.
BACKGROUND: Several studies have examined intellectual functioning of boys with duchenne muscular dystrophy (DMD). However, little is known about the remaining cognitive weaknesses in adults with DMD. OBJECTIVE: The purpose of this study was to investigate the profile of cognitive functioning that is characteristics of adults with DMD. METHODS: Twenty-four subscales from the Wechsler Adult Intelligence Scale III (WAIS-III), the Clinical Assessment for Attention (CAT), and the Wechsler Memory Scale Revised (WMS-R) were used to assess participants with DMD (N=15; mean age=30.4years). RESULTS: Scores for Picture Completion, Arithmetic, Matrix Reasoning, Symbol Search, Letter-Number Sequencing, and Digit Span of the WAIS-III; all CAT scores, and Logical Memory and Delayed Logical Memory from the WMS-R were significantly deficient in adults with DMD in comparison to the normal population. CONCLUSION: The ability to sequentially process auditory and visual information remains impaired in adults with DMD.
Authors: Marco Orsini; Ana Carolina; Andorinho de F Ferreira; Anna Carolina Damm de Assis; Thais Magalhães; Silmar Teixeira; Victor Hugo Bastos; Victor Marinho; Thomaz Oliveira; Rossano Fiorelli; Acary Bulle Oliveira; Marcos R G de Freitas Journal: Neurol Int Date: 2018-07-04
Authors: Kostas Nizamis; Wouter Schutte; Jan J Grutters; Jasper Goseling; Noortje H M Rijken; Bart F J M Koopman Journal: PLoS One Date: 2020-01-31 Impact factor: 3.240
Authors: R Quinlivan; B Messer; P Murphy; R Astin; R Mukherjee; J Khan; A Emmanuel; S C Wong; R Kulshresha; T Willis; J Pattni; D Willis; A Morgan; K Savvatis; R Keen; J Bourke; C Marini Bettolo; C Hewamadduma Journal: J Neuromuscul Dis Date: 2021