Literature DB >> 27825086

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin.

Han C Dan, Mei Sun, Lin Yang, Richard I Feldman, Xue-Mei Sui, Chien Chen Ou, Mark Nellist, Raymond S Yeung, Dicky J J Halley, Santo V Nicosia, Warren J Pledger, Jin Q Cheng.   

Abstract

Entities:  

Year:  2016        PMID： 27825086      PMCID： PMC5077223          DOI： 10.1074/jbc.A116.205838

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  2 in total

Review 1.  Revisiting Brain Tuberous Sclerosis Complex in Rat and Human: Shared Molecular and Cellular Pathology Leads to Distinct Neurophysiological and Behavioral Phenotypes.

Authors:  Viera Kútna; Valerie B O'Leary; Ehren Newman; Cyril Hoschl; Saak V Ovsepian
Journal:  Neurotherapeutics       Date:  2021-01-04       Impact factor: 7.620

2.  Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo.

Authors:  Min Chen; Jian Lu; Wei Wei; Ying Lv; Xiaoqi Zhang; Yuling Yao; Lei Wang; Tingsheng Ling; Xiaoping Zou
Journal:  Onco Targets Ther       Date:  2018-10-10       Impact factor: 4.147
  2 in total

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