Pilar Pérez-Ros1, Francisco M Martinez-Arnau2, Vincenzo Malafarina3, Francisco J Tarazona-Santabalbina4. 1. Nursing Faculty, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain. Electronic address: pilar.perez@ucv.es. 2. Nursing Faculty, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain; Department of Physiotherapy, Universitat de Valencia, Spain. 3. Department of Geriatrics, Complejo Hospitalario de Navarra, Pamplona, Spain; Department of Nutrition, Food Science and Physiology, School of Pharmacy, Universidad de Navarra, Pamplona, Spain. 4. Nursing Faculty, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain; Department of Geriatrics, Hospital Universitario de la Ribera, Valencia, Spain.
Abstract
BACKGROUND: The risk of falls increases with age. Balance alteration and polypharmacy are independent contributors to an increased risk of falls. OBJECTIVE: The primary aim was to assess whether a proprioceptive exercise programme reduces the incidence of falls. A secondary aim was to assess the association between drugs and falls. DESIGN: This was a before-after non-randomised intervention study. PARTICIPANTS: The study recruited independent and cognitively intact community-dwelling people aged over 69 years, from December 2012 to May 2014. METHODS: The intervention was done by a nurse and consisted of a monthly supervised group session of proprioceptive training for 1 year, supplemented by a home diary exercise. Daily medication was reviewed. RESULTS: We included 572 subjects (63.3% women), mean age 76.1±3.9 years. The mean number of drugs prescribed at the start of the study was 4.7±3.0and 353 of the participants (61.7%) were taking four or more drugs a day. The elderly who fell were more dependent in their activities of daily living (Barthel index), and their balance was worse (determined using the Tinetti scale), as were their results on a cognitive scale (the MEC). After the intervention, an increase in self-perceived quality of life (EQ5D) was reported. The incidence of falls was reduced from 37.5% in the 12 months prior to the intervention to 25.7% in the 12 months after the intervention. During the follow-up, beta-blocker use was associated with an increased incidence of falls (OR=2.05; 95%IC: 1.24-3.39; p=0.005). In contrast, antiplatelet/anticoagulation drugs were associated with a lower risk of falls (OR=0.7; 95%IC: 0.55-0.88; p=0.003). CONCLUSIONS: The proprioceptive exercise programme reduced the incidence of falls in community-dwelling older people. Multiple drug use was an independent predictor of an increased risk of falls, and specific drug groups were associated with falls.
BACKGROUND: The risk of falls increases with age. Balance alteration and polypharmacy are independent contributors to an increased risk of falls. OBJECTIVE: The primary aim was to assess whether a proprioceptive exercise programme reduces the incidence of falls. A secondary aim was to assess the association between drugs and falls. DESIGN: This was a before-after non-randomised intervention study. PARTICIPANTS: The study recruited independent and cognitively intact community-dwelling people aged over 69 years, from December 2012 to May 2014. METHODS: The intervention was done by a nurse and consisted of a monthly supervised group session of proprioceptive training for 1 year, supplemented by a home diary exercise. Daily medication was reviewed. RESULTS: We included 572 subjects (63.3% women), mean age 76.1±3.9 years. The mean number of drugs prescribed at the start of the study was 4.7±3.0and 353 of the participants (61.7%) were taking four or more drugs a day. The elderly who fell were more dependent in their activities of daily living (Barthel index), and their balance was worse (determined using the Tinetti scale), as were their results on a cognitive scale (the MEC). After the intervention, an increase in self-perceived quality of life (EQ5D) was reported. The incidence of falls was reduced from 37.5% in the 12 months prior to the intervention to 25.7% in the 12 months after the intervention. During the follow-up, beta-blocker use was associated with an increased incidence of falls (OR=2.05; 95%IC: 1.24-3.39; p=0.005). In contrast, antiplatelet/anticoagulation drugs were associated with a lower risk of falls (OR=0.7; 95%IC: 0.55-0.88; p=0.003). CONCLUSIONS: The proprioceptive exercise programme reduced the incidence of falls in community-dwelling older people. Multiple drug use was an independent predictor of an increased risk of falls, and specific drug groups were associated with falls.